|Description||Alosetron, an effective 5-HT3 receptor antagonist, could be commonly used against irritable bowel syndrome.|
The hydrochloride salt form of Ziprasidone which is an antagonism of both serotonin and dopamine receptor and could be effective against schizophrenia.
This active molecular is a Selective 5-HT6 Receptor antagonist, for the treatment of Alzheimer's Disease under development by by Avineuro Pharmaceuticals. AVN-2...
Thioproperazine is a potent neuroleptic with antipsychotic properties, for the treatment of all types of acute and chronic schizophrenia, including those which ...
SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other recept...
GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron bind...
Citalopram Hydrobromide is an inhibitor of serotonin (5-HT) uptake used as an antidepressant.
Quetiapine, an thiazepin-analogue of Clozapine, could be effective in the treatment for schizophrenia and major depressive disorder for behaving as a 5HT-2 and ...
Mosapride, a selective agonist of 5-HT4 receptor, could be used as a astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist.
Pardoprunox, also called as SLV308 or DU-126891, is a D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A rec...
LY 302148 is a 5-HT1F receptor agonist with potential for migraine therapeutics.
Thesuccinate salt form of Frovatriptan, a carbazole derivative, has been found to be a 5-HT receptor agonist that could be used as an antimigraine agent.
Granisetron is an antagonist of serptpmom 5-HT3 receptor and could be used to relieve the nausea and vomiting symptom after receving chemotherapy by decreasing ...
SB-242084 HCl salt
SB-242084 is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor. It can increase the effectiveness of the sel...
The mesylate salt form of Dolasetron which is a pseudopelletierine derivative and could be used to relieve the nausea and vomiting caused by chemotherapy for be...
BRL-15572 displays high affinity and selectivity for h5-HT1D receptors. BRL-15572 has 60-fold higher affinity for h5-HT1D than 5-HT1B receptors.
Way 100135 is a selective 5-HT1A receptor antagonist originated by Wyeth with IC50 value of 15 nM. IC 50 values for 5-HT1B, 1C, 2,α1, α2 and D2 receptors are ov...
Trimipramine Maleate is a tricyclic antidepressant for the treatment of depression and depression accompanied by anxiety.
LY 215840 is a potent antagonist of both Serotonin 2A receptor and Serotonin 7 receptor. It can reduce stimulatory effect of serotonin on aldosterone secretion ...
Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.
Naratriptan D3 Hydrochloride
The hydrochloride salt form of isotope labelled Naratriptan which is a selective 5-HT1 receptor agonist and could be used against migraine headaches.