1.The bile acid Deoxycholate Elicits defenses in Arabidopsis and reduces bacterial infection.
Zarattini M1,2, Launay A1,3, Farjad M1, Wénès E1, Taconnat L4, Boutet S1, Bernacchia G2, Fagard M1. Mol Plant Pathol. 2016 Apr 16. doi: 10.1111/mpp.12416. [Epub ahead of print]
Crop yield loss is significantly affected by disease. Considering that the worldwide demand for agricultural products is increasing, there is a need to pursue the development of new methods to protect crops from disease. One mechanism of plant protection is through the activation of its immune system. By exogenous application, "plant activator molecules" with elicitor properties, can be used to activate the plant immune system. These defense-inducing molecules represent a powerful and often environment-friendly toolset to fight pathogens. We show that the secondary bile acid deoxycholic acid (DCA) induces defense in Arabidopsis and reduces the proliferation of two bacterial phytopathogens, Erwinia amylovora and Pseudomonas syringae pv. tomato. We describe the global defense response triggered by this new plant activator in Arabidopsis at the transcriptional level. Several induced genes were selected for further analysis by qRT-PCR: we describe the kinetics of their induction and we show that abiotic stress, such as moderate drought or nitrogen limitation, does not impede DCA induction of defense.
2.Work ability among Finnish workers with type 1 diabetes.
Hakkarainen P1, Moilanen L2, Hänninen V3, Heikkinen J4, Räsänen K4. Occup Med (Lond). 2016 Apr 16. pii: kqw053. [Epub ahead of print]
BACKGROUND: Work ability represents the balance between individual resources, health status and job demands. As far as we are aware, these issues have not been examined in working people with type 1 diabetes (T1D).
3.BioGlue for traumatic liver laceration.
Daniele E1, Dissanaike S2. Int J Surg Case Rep. 2016 Apr 6;23:33-35. doi: 10.1016/j.ijscr.2016.03.039. [Epub ahead of print]
INTRODUCTION: Advances in diagnostic imaging and monitoring have led to a shift towards primary non-operative management for most blunt liver injuries. Hemostatic biologic agents are a potential adjunct in the treatment of bile leak, especially in patients requiring surgery for drainage of a biloma.
4.Total parathyroidectomy with autotransplantation versus subtotal parathyroidectomy for renal hyperparathyroidism: a systematic review and meta-analysis.
Chen J1, Jia X1, Kong X1, Wang Z1, Cui M1, Xu D1. Nephrology (Carlton). 2016 Apr 16. doi: 10.1111/nep.12801. [Epub ahead of print]
OBJECTIVE: Total parathyroidectomy with autotransplantation(TPTX+AT) and subtotal parathyroidectomy(SPTX) have been recommended to patients with renal hyperparathyroidism(RHPT).But which one is the best surgical method remains controversial. The aim of the present study was to compare the two surgical procedures with respect to long-term outcomes.