ALK inhibitor 1 - CAS 761436-81-1
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
ALK inhibitor 1
Catalog Number:
761436-81-1
Synonyms:
Benzenesulfonamide, 2-[[5-bromo-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-
CAS Number:
761436-81-1
Description:
ALK inhibitor 1 is a novel and selective inhibitor for the ALK kinase.
Molecular Weight:
562.48
Molecular Formula:
C23H28BrN7O3S
COA:
Inquire
MSDS:
Inquire
Targets:
ALK
Chemical Structure
CAS 761436-81-1 ALK inhibitor 1

Related ALK Products


Entrectinib (RXDX-101)
(CAS: 1108743-60-7)

Entrectinib (RXDX-101) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Phase 2.

CAS 1062368-49-3 ML347

ML347
(CAS: 1062368-49-3)

ML347 is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM.

Brigatinib (AP-26113)
(CAS: 1197953-54-0)

Brigatinib, is an orally active, also known as AP-26113, potent and selective Dual ALK/EGFR inhibitor. AP26113 binds to and inhibits ALK kinase(ALK belongs to t...

CAS 1116235-97-2 GSK1838705A

GSK1838705A
(CAS: 1116235-97-2)

GSK1838705A is a small-molecule kinase inhibitor that inhibits IGF-IR and IR (insulin receptor) with IC50s of 2.0 and 1.6 nM, respectively. GSK1838705A blocks ...

CAS 1454846-35-5 PF-06463922

PF-06463922
(CAS: 1454846-35-5)

PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), wi...

CAS 1627503-67-6 LDN-214117

LDN-214117
(CAS: 1627503-67-6)

LDN-214117 is a selective and potent ALK2 inhibitor. LDN-214117 inhibited ALK2 most, with a biochemical IC50 of 24 nM. There are currently no effective therapi...

CAS 1062368-24-4 LDN193189

LDN193189
(CAS: 1062368-24-4)

LDN193189 is a selective and potent ALK inhibitor with potential anticancer activity.

CAS 356559-13-2 SB-505124 hydrochloride

SB-505124 hydrochloride
(CAS: 356559-13-2)

SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptor ALK5 and as well as being a selective inhibitor of ALK4 but with less pote...

CAS 1022958-60-6 CEP-28122

CEP-28122
(CAS: 1022958-60-6)

CEP-28122 is a Highly Potent and Selective Orally Active Inhibitor of Anaplastic Lymphoma Kinase with Antitumor Activity in Experimental Models of Human Cancers...

CAS 761436-81-1 ALK inhibitor 1

ALK inhibitor 1
(CAS: 761436-81-1)

ALK inhibitor 1 is a novel and selective inhibitor for the ALK kinase.

CAS 1415560-69-8 Crizotinib hydrochloride

Crizotinib hydrochloride
(CAS: 1415560-69-8)

Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK. Crizotinib inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM). Crizotinib is use...

CAS 1356962-34-9 HG-14-10-04

HG-14-10-04
(CAS: 1356962-34-9)

HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.

Belizatinib
(CAS: 1357920-84-3)

Belizatinib is inhibitor of both anaplastic lymphoma kinase (ALK) and tropomyosin-related kinases (TRK). Belizatinib can bind to and inhibit both ALK and TRK ki...

CAS 1356962-20-3 AZD-3463

AZD-3463
(CAS: 1356962-20-3)

AZD-3463 is a potent ALK/IGF1R inhibitor with potential anticancer activity.

CAS 761438-38-4 ALK inhibitor 2

ALK inhibitor 2
(CAS: 761438-38-4)

ALK inhibitor 2 is a novel and selective inhibitor for the ALK kinase.

CAS 1197958-12-5 AP-26113

AP-26113
(CAS: 1197958-12-5)

AP26113 is an orally available inhibitor of receptor tyrosine kinases anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) with pote...

CAS 1256580-46-7 Alectinib

Alectinib
(CAS: 1256580-46-7)

Alectinib, also known as AF802, or CH5424802 or RO5424802, is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing ...

IN-1130
(CAS: 868612-83-3)

IN-1130 is a selective ALK5 inhibitor with >100 fold selectivity over p38α and a panel of 26 other serine/threonine and tyrosine kinases. It also inhibit phosph...

R-268712
(CAS: 879487-87-3)

R-268712 is a potent and selective inhibitor of TGF-β type I receptor/ALK5 with an IC50 of 2.5 nM, an approximately 5000-fold more selectivity for ALK5 than p38...

CAS 1431985-92-0 K02288

K02288
(CAS: 1431985-92-0)

K02288 is a highly selective 2-aminopyridinebased inhibitor K02288 with in vitro activity against ALK2 at low nanomolar concentrations similar to the current le...