Alibendol - CAS 26750-81-2
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
Alibendol
Catalog Number:
26750-81-2
Synonyms:
EB 1856
CAS Number:
26750-81-2
Description:
Alibendol is an antispasmodic,choleretic, and cholekinetic.
Molecular Weight:
251.28
Molecular Formula:
C13H17NO4
COA:
Inquire
MSDS:
Inquire
Targets:
Others
Chemical Structure
CAS 26750-81-2 Alibendol

Related Products


CAS 58546-56-8 Schisantherin A

Schisantherin A
(CAS: 58546-56-8)

Schisantherin A, source from the seeds of Schisandra chinensis (Turcz.) Baill., is a mechanism-based inhibitor that not only competitively inhibits but irrevers...

CP 46665
(CAS: 72618-10-1)

CP 46665 is Immunomodulator. But it is lack of therapeutic activity in rodent tumors and human non-seminomatous germ cell tumors growing in nude mice.

CAS 14919-77-8 Benserazide HCl

Benserazide HCl
(CAS: 14919-77-8)

Benserazide HCl is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.

AT-584
(CAS: 16810-17-6)

AT-584, an azoniatricyclo compound, could have potential biological activity in pharmaceutical studies.

CAS 63223-86-9 Ginsenoside Rh1

Ginsenoside Rh1
(CAS: 63223-86-9)

Ginsenoside Rg1, the predominant ginsenoside in the rhizome,shows no hemolytic nor cytotoxic activities.It acts as a weak phytoestrogen, presumably by binding a...

CAS 1093659-90-5 Ezetimibe D4

Ezetimibe D4
(CAS: 1093659-90-5)

Ezetimibe D4 is a deuterium labeled Ezetimibe, which is a cholesterol-absorption inhibitor and reduces levels of low-density lipoprotein (LDL) cholesterol.

CAS 105558-26-7 Ginsenoside Rh3

Ginsenoside Rh3
(CAS: 105558-26-7)

Ginsenoside Rh3 is isolated from red ginseng and metabolized from ginsenoside Rg5 and could be used as an anti-inflammatory agent.

CAS 1115-70-4 Metformin HCl

Metformin HCl
(CAS: 1115-70-4)

Metformin decreases hyperglycemia primarily by suppressing glucose production by the liver (hepatic gluconeogenesis).

FR-168888 Free Base
(CAS: 168620-45-9)

The free base of FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia ther...

CHF 1255
(CAS: 146728-52-1)

CHF 1255, a tetrahydronaphthalen derivative, has been found to be probably effective against heart failure.

CP-608039
(CAS: 331727-55-0)

CP-608039 is a selective adenosine A3 receptor agonist with 1,260-fold selectivity for the human A3 versus human A1 receptor.

CAS 120138-50-3 Quinupristin

Quinupristin
(CAS: 120138-50-3)

Quinupristin is an antibiotic agent and usually used in combination with dalfopristin The trade name is Synercid. It is active against Gram-positive bacteria th...

CAS 1453097-13-6 HUHS015

HUHS015
(CAS: 1453097-13-6)

HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. As expect...

CAS 106791-40-6 Mivacurium

Mivacurium
(CAS: 106791-40-6)

Mivacurium is a bisbenzylisoquinolinium based and a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. It binds competitiv...

CAS 33173-53-4 4-Azido-L-phenylalanine

4-Azido-L-phenylalanine
(CAS: 33173-53-4)

4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine. It is a nonpolar, essential amino acid that naturally occurs in the human body and is als...

T-3364366
(CAS: 1356354-09-0)

T-3364366 is a reversible and slow-binding Delta-5 desaturase (D5D) inhibitor. Ki is less than 2.7 nM and a dissociation half-life is more than 2.0 h. D5D is an...

GSK-114
(CAS: 1301761-96-5)

GSK-114 is a selective TNNI3 Interacting Kinase (TNNI3K) inhibitor with IC50 of 25nM. GSK-114 shows significant bias for TNNI3K over B-Raf, exceptional broad sp...

CP-5484
(CAS: 352308-27-1)

CP-5484 is a synthetic bio-active chemical with potent anti-MRSA activity and low acute toxicity.

CAS 472-61-7 Astaxanthin

Astaxanthin
(CAS: 472-61-7)

Carotenoid pigment found mostly in animal organisms, but also occuring in plants; thought to be the precursor of astacin. Astaxanthin is a carotenoid pigment fo...

CAS 1161233-85-7 BTZ043

BTZ043
(CAS: 1161233-85-7)

The new antitubercular drug candidate 2-[2-S-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one (BTZ043) targets th...

Reference Reading


1. A sensitive, acetonitrile-free, HPLC method for determination of alibendol in dog plasma and its application to pharmacokinetic studies
Jae Kuk Ryu. Journal of Pharmaceutical Investigation (2012) 42:185–190
Alibendol, or 5-allyl-2-hydroxy-N-(2-hydroxyethyl)-3-methoxybenzamide, is known as an active pharmaceutical ingredient in antispasmodic, choleretic, and cholekinetic medications. This drug is useful for the treatment of dyspepsia due to biliary insufficiency, alimentary intolerance,and constipation of hepatic origin (Kim et al. 2004; Song et al. 2010). To date, only one method to assess alibendol levels in plasma has been reported in the literature (Song et al. 2010). However, this method uses acetonitrile as a mobile phase. Because acetonitrile is obtained as a co-product in the production of acrylonitrile, many industries are experiencing a shortage of acetonitrile (Venkatasami and Sowa 2010). This ongoing acetonitrile shortage has forced chemists to replace acetonitrile with more readily available solvents, such as methanol. To date, this is the first report of an acetonitrile-free high performance liquid chromatography (HPLC) method for the determination of alibendol in biological fluids. The method previously reported by Song et al. (2010) achieved an LLOQ of 50 ng/ml. Thus, that method may lack the sensitivity needed to determine the low plasma concentrations encountered in pharmaco- kinetic studies. Furthermore, that report is written in Korean, so it may be difficult for non-Koreans to use that method.