|Description||Albiflorin is a major constituent presents in peony root, which possesses therapeutic potential for neurodegenerative diseases.|
GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-29...
The hydrochloride salt form of Emixustat which could effectively inhibit the production of 11-cis-retinol which is related to age-related macular degeneration.
Oxtriphylline is a cough medicine derived from xanthine used in the treatment for chronic asthma.
Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various d...
4-Aminohippuric acid is a typical substrate of organic anion transport systems.
Psoralen is an active ingredient from Fructus Psoraleae and has anticancer activity.
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)
LY 189332 is a bio-active molecular under the development of Eli Lilly as an antimetastatic drug.
Midodrine is an α1-receptor agonist and exerts its actions via activation of the alpha-adrenergic receptors of the arteriolar and venous vasculature.
Eprociclovir, an acyclovir analogue, has been found to have antiviral activity especially against herpes virus.
BMS 182264 is a bio-active chemical, but few detailed information has been published yet.
PLX-7683, a pyrrolopyridine derivative, has been found to be a paradox breaker that was studied to exhibit more durable efficacy and better safety than some for...
Pyriproxyfen is a pyridine-based pesticide which is effective against a variety of arthropoda, in particular to protect cotton crops against whitefly. It is a j...
Quercetin, a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. Ph...
Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthes...
Mice treated with vehicle showed significantly enlarged tumors, whereas mice treated with YL-109 showed attenuated tumor growth using MCF-7 cells. Interestingly...
GSK2194069 is a fatty acid synthase (FAS) inhibitor. GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS with an IC5...
Hydroxy Itraconazole, a metabolite of Itraconazole, is a ketoconazole analogue which could be used as an antimycotic.
Ingenol disoxate is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties. Ingenol is a natural product found in the sap of the plant Euphorb...
Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is...