|Synonyms||2,3-Dihydro-7-methoxy-α-oxo-1,4-benzothiazepine-4(5H)-acetic Acid; ARM 036; Aladorian; S 36; S 44121-1|
|Description||Aladorianis is a ryanodine receptor calcium release channel modulator. It is an antiarrhythmic agent. Clinical development for Chronic heart failure and Ventricular tachycardia was discontinued.|
|Quality Standard||In-house standard|
|Current Developer||ARMGO Pharma; Servier|
NC-174 is a trisubstituted guanidine high potency synthetic sweetener.
Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM.
Carotenoid pigment found mostly in animal organisms, but also occuring in plants; thought to be the precursor of astacin. Astaxanthin is a carotenoid pigment fo...
trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a well-known fatty acid synthase (FAS) inhibitor. Studies show that trans-Tetrahydro-4-meth...
Penicillamine is used as an antirheumatic and as a chelating agent in Wilson’s disease.
CVT-3369, a piperazineacetic acid derivative, is probably effective in some of biological studies.
BPH-652, also known as BMS-187745, has been found to be a SQS inhibitor that could probably be effective against S. aureus infections.
Acarbose is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.
Succinyl phosphonate was found to be effective inhibitors of alpha-ketoglutarate oxidative decarboxylation, catalyzed by both muscle and bacterial alpha-ketoglu...
This active molecular is a selective peptide deformylase inhibitor. It has good anti-bacteria activity in vitro. Antibacterial spectrum of Lanopepden includes S...
Quetiapine metabolite Quetiapine sulfoxi
Quetiapine metabolite Quetiapine sulfoxide, a metabolite of Quetiapine, has antipsychotic effect.
GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. It can produce long-term or total regression of adenomatous, but only marginal growth ...
Metformin decreases hyperglycemia primarily by suppressing glucose production by the liver (hepatic gluconeogenesis).
Extract from Carthamin, widely used for the treatment of acute ischemic stroke by acting directly on BV2 microglia.
CB 3703 is an inhibitor of hydrofolate reductase.
ML281, a quinoxalin derivative, has been found to be a STK33 inhibitor and could have probable effect against KRAS-dependent cancers. IC50: 14 nM.
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, ...
This active molecular can be applicated as a photosensitizer for PDT (Photodynamic Therapy) of cancer. Redaporfin showed a great efficacy in the treatment of ma...
Silibinin (INN), also known as silybin, is the major active constituent of silymarin, standardized extract of the milk thistle seeds, containing mixture of flav...