AKT inhibitor VIII - CAS 612847-09-3
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
AKT inhibitor VIII
Catalog Number:
612847-09-3
Synonyms:
2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-
CAS Number:
612847-09-3
Description:
Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity. It does not exhibit any inhibitory effect against pleckstrin homology (PH) domain-lacking Akts, AGC family kinases, PKA, PKC or SGK. It also prevails over Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and has been shown to block basal and stimulated phosphorylation/activation of Akt1/Akt2 in cultured cells and in mice.
Molecular Weight:
551.64
Molecular Formula:
C34H29N7O
COA:
Inquire
MSDS:
Inquire
Targets:
Akt
Chemical Structure
CAS 612847-09-3 AKT inhibitor VIII

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