Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin ...
Seco-Duocarmycin CN is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviol...
Tropane alkaloid, from plants of the Convolvulus genus,
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion
An antineoplastic alkaloid from Colchicum autumnale L. isolated from Colchicum autumnale L.
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
It was the main alkaloid found in medicinal plants Datura metel. .
Chlorotoxin (Cltx) is a neurotoxin that was originally isolated from the venom of Leiurus quinquestriatus. Chlorotoxin is a specific ligand of glioma cells. Chl...
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Synthetic, an inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
A natural compound extracted from Phellodendron chinense, exhibits a near planar framework
Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A potent medium-lasting selective M2 muscarinic receptor antagonist.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
An anticonvulsant which reduces motor activity, enhances the effects of alcohol, ether and barbiturates. Quinoline alkaloid , from plants of the Rutaceae family...
β-Pompilidotoxin slows the inactivation of neuronal Navs. β-Pompilidotoxin was isolated from the venoms of two wasps, Anoplius amariensis and Batozonellus macul...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.