|Description||AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.|
1-O-Acetylbritannilactone significantly reduced melanin production in a dose-dependent manner with IC50 value of 13.3 uM. inhibited melanogenesis by activating ...
PX-12 is an irreversible inhibitor of Trx-1 currently in clinical development as an antitumor agent. The research results suggest that the lowering of elevated ...
Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease. It consists of polyallylamine that is crosslinked...
Duloxetine is a serotonin-norepinephrine reuptake inhibitor (Ki=4.6 nM), used for major depressive disorder, generalized anxiety disorder, fibromyalgia and neur...
4E1RCat is a dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction, and inhibits the binding of eIF4G to eIF4E with IC50 of 3.2 μM.
OKT3-induced PBMC proliferation was inhibited by octahydrocurcumin with IC50 of 82 uM. The investigated substances with the strongest effect on radical scavengi...
ATR-101 is a selective Acetyl CoA C-acetyltransferase inhibitor. ATR-101 is uniquely distributed to adrenal tissues and inhibition of adrenal ACAT1 by ATR-101 d...
Nanofin is neuropathic blocker used for mild to moderate hypertension.
Pyriproxyfen is a pyridine-based pesticide which is effective against a variety of arthropoda, in particular to protect cotton crops against whitefly. It is a j...
Gemcadiol is a new antilipemic drug with lipid-regulating properties.
Endochin is an experimental antimalarial which was known to be causal prophylactic and potent erythrocytic stage agents in avian models.
Ginsenoside Rh3 is isolated from red ginseng and metabolized from ginsenoside Rg5 and could be used as an anti-inflammatory agent.
GK921 is a transglutaminase 2 (TGase 2) inhibitor with average GI50 of 0.9 μM in cancer cell lines.
O4I1 is a potent inducer of Oct3/4. O4I1 enhanced Oct3/4 expression. O4I1 not only promoted expression and stabilization of Oct3/4 but also enhanced its transcr...
Dihydrochelerythrine is a natural compound isolated from the leaves of Macleaya microcarpa, which has antifungal activity.
Omeprazole sulphide is a metabolite of Omeprazole. It is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazo...
Sanguinarine chloride hydrate
Sanguinarine is a benzylisoquinoline alkaloid isolated from Papaveraceae with antimicrobial, anti-inflammatory, and anti-oxidant properties.
Ligustilide not only has an active dilatory effect on myometrium but also an effective role in reducing the neurogenic and inflammatory pain, thus having the po...
Rehmannioside D is a carotenoid glycoside extracted from the roots of Rehmannia glutinosa.
Botanical Source from Bufo bufo gargarizans and Bufo formosus, used for microbial transformation.