AHU-377 - CAS 149709-62-6
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
AHU-377
Catalog Number:
149709-62-6
Synonyms:
Sacubitril; AHU 377; AHU377
CAS Number:
149709-62-6
Description:
Sacubitril, also known as AHU377 or LCZ696, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.
Molecular Weight:
411.49
Molecular Formula:
C24H29NO5
COA:
Inquire
MSDS:
Inquire
Targets:
Neprilysin
Chemical Structure
CAS 149709-62-6 AHU-377

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