|Product Name||Agomelatine L(+)-Tartaric acid|
|Synonyms||Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-,(2R,3R)-2,3-dihydroxybutanedioate;S-20098 L(+)-Tartaric acid|
|Description||Agomelatine L(+)-Tartaric acid is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. It is used as an antidepressant drug. It has been approved by FDA in October 2011. It has toxicities, such as Hyperhidrosis, Abdominal pain, Nausea, Vomiting, Diarrhoea, Constipation, Back pain, Fatigue and so on.|
|Quality Standard||In-house standard|
Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM ...
Pindolol, an Indole derivative, could be used in the treatment of hypertension and arrhythmia for acting as a 5-HT1A/1B receptor antagonist. IC50: 33nM(Ki).
Ferulic acid sodium
Ferulic acid sodium is one of the most abundant phenolic acids ubiquitously existing in plants. Free ferulic acid is a good antioxidant since it forms a resonan...
LY 125180 is a serotonin antagonist.It can effect on serotonin uptake and serotonin synthesis in rat brain in vitro and in vivo.
The hydrochloride salt form of CP-809101 which is a selective 5-HT2C receptor agonist which probably shows antipsychotic activity and restrains amphetamine-stim...
The hydrochloride salt form of Ziprasidone which is an antagonism of both serotonin and dopamine receptor and could be effective against schizophrenia.
The hydrochloride salt form of Sarpogrelate, a 5-HT2 antagonist, could be used as an antiplatelet agent and other sorts of disease like angina pectoris, diabete...
Revexepride, also referred as SSP-002358, is a very selective and potent 5-HT4 receptor agonist and a novel prokinetic that stimulates gastrointestinal motility...
Elzasonan citrate is a selective 5-hydroxytryptamine 1B receptor antagonist for treat patients with major depressive disorder and obsessive compulsive disorder.
This active molecular is a Selective 5-HT6 Receptor antagonist, for the treatment of Alzheimer's Disease under development by by Avineuro Pharmaceuticals. AVN-2...
Nelotanser is Serotonin 2A receptor inverse agonist. In Aug 2016, Axovant Sciences initiated a phase-II clinical trial in Lewy body disease in USA.
PR-073 is a novel 5-HT7 antagonist, which can inhibit immune responses and treat inflammatory bowel disease (IBD). Preclinical studies demonstrated that PR-073 ...
SUVN-502 is a 5-HT6 receptor antagonist originated by Suven Life Sciences. It has >1200-fold selectivity over 5-HT2A receptor with a superior profile that diffe...
Lu AE58054 HCl salt
Lu AE58054 hydrochloride is an in-vitro potency and selectivity, in-vivo binding affinity and effect of the 5-HT(6)R antagonist with a Ki value of 0.83 nM.
The hydrobromide salt form of NAN-190 which is an effective antagonist of 5-HT1A serotonin receptor.
Dolasetron, a pseudopelletierine derivative, is a 5-HT3 receptor antagonist that could be used to relieve the nausea and vomiting caused by chemotherapy.
Quetiapine D4 fumarate
The isotope labelled form of Quetiapine fumarate, a 5-HT receptor antagonist, is widely used as an antipsychotic drug.
Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor. It is used mainly as a...
MK212 is a 5HT2C-receptor agonist. It exhibited anxiolytic activity in mice at low doses. It is a serotonin agonist. It could promote the secretion of serum pro...
BMS 181101, an indole derivative, has been found to be a 5-HT receptor agonist that could be probably effective against depression and also restrain serotonin r...