AG 205 - CAS 442656-02-2
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
AG 205
Catalog Number:
442656-02-2
Synonyms:
1-[(4aR,9bS)-2,8-dimethyl-3,4,4a,9b-tetrahydro-1H-pyrido[4,3-b]indol-5-yl]-2-[1-(4-chlorophenyl)tetrazol-5-yl]sulfanylethanone;
CAS Number:
442656-02-2
Description:
AG-205 is a novel Pgrmc1 (progesterone receptor membrane component 1) inhibitor, alters the spectroscopic properties of the Pgrmc1-heme complex.
Molecular Weight:
454.98
Molecular Formula:
C22H23ClN6OS
Quantity:
Milligrams-Grams
Quality Standard:
Enterprise standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
CC1=CC2=C(C=C1)N(C3C2CN(CC3)C)C(=O)CSC4=NN=NN4C5=CC=C(C=C5)Cl
InChI:
1S/C22H23ClN6OS/c1-14-3-8-19-17(11-14)18-12-27(2)10-9-20(18)28(19)21(30)13-31-22-24-25-26-29(22)16-6-4-15(23)5-7-16/h3-8,11,18,20H,9-10,12-13H2,1-2H3/t18-,20-/m1/s1
InChIKey:
GJNBAISSZRNGTM-UYAOXDASSA-N
Targets:
Progesterone Receptor

Related Progesterone Receptor Products


CAS 520-85-4 Medroxy Progesterone

Medroxy Progesterone
(CAS: 520-85-4)

Medroxy Progesterone is an orally active progestogen used in hormone replacement therepy (HRT).

CAS 297-76-7 Ethynodiol diacetate

Ethynodiol diacetate
(CAS: 297-76-7)

Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills.Relative to other 19-nortestosterone derivatives, it has relatively ...

CAS 152-62-5 Dydrogesterone

Dydrogesterone
(CAS: 152-62-5)

Dydrogesterone is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.

CAS 126784-99-4 Ulipristal Acetate

Ulipristal Acetate
(CAS: 126784-99-4)

Ulipristal Acetate is an orally bioactive and selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. It binds to...

CAS 60282-87-3 Gestodene

Gestodene
(CAS: 60282-87-3)

Gestodene is a progestogen hormonal contraceptive.Gestodene is androgenically neutral, meaning that contraceptive pills containing gestodene do not exhibit the ...

AG 205
(CAS: 442656-02-2)

AG-205 is a novel Pgrmc1 (progesterone receptor membrane component 1) inhibitor, alters the spectroscopic properties of the Pgrmc1-heme complex.

CAS 7759-35-5 Nestoron

Nestoron
(CAS: 7759-35-5)

Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent...

Vilaprisan
(CAS: 1262108-14-4)

Vilaprisan is a selective oral progesterone receptor antagonist under the development of Bayer HealthCare Pharmaceuticals. BAY 1002670 showed a marked dose-depe...

CAS 797-63-7 Levonorgestrel

Levonorgestrel
(CAS: 797-63-7)

Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.

CAS 84371-65-3 Mifepristone

Mifepristone
(CAS: 84371-65-3)

Mifepristone is a progesterone receptor antagonist(IC50= 0.2 nM) and a glucocorticoid receptor antagonist(IC50= 2.6 nM). It is used as an abortifacient in the f...

CAS 68-22-4 Norethindrone

Norethindrone
(CAS: 68-22-4)

Norethindrone, a synthetic progestin, is an oral contraceptive involved in the inhibition of cytosolic sulfotransferases (SULT).

CAS 850-52-2 Altrenogest

Altrenogest
(CAS: 850-52-2)

Altrenogest is a progestogen structurally related to veterinary steroid trenbolone.

CP-8668
(CAS: 209331-43-1)

CP-8668 is an orally active nonsteroidal progesterone receptor modulator with no significant affinity for human glucocorticoid receptor or human estrogen recept...

JNJ-1250132
(CAS: 240805-96-3)

JNJ-1250132, a new steroidal progestin antagonist, inhibits binding of the receptor to DNA in vitro. JNJ-1250132 induces a receptor conformation more similar to...

CAS 67392-87-4 Drospirenone

Drospirenone
(CAS: 67392-87-4)

Drospirenone is a synthetic hormone used in birth control pills and postmenopausal hormone replacement therapy pills.

CAS 302-22-7 Chlormadinone acetate

Chlormadinone acetate
(CAS: 302-22-7)

Chlormadinone acetate, with antiandrogen and antiestrogenic activities it is a steroidal progestin used in combinations as an oral contraceptive.

CAS 71-58-9 Medroxyprogesterone acetate

Medroxyprogesterone acetate
(CAS: 71-58-9)

Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.

CAS 57-83-0 Progesterone

Progesterone
(CAS: 57-83-0)

Progesterone, synthesized from cholesterol by the sequential action of desmolase in the mitochondria, plays an important role in brain function as a endogenous ...

CAS 65928-58-7 Dienogest

Dienogest
(CAS: 65928-58-7)

Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.

Telapristone acetate
(CAS: 198414-31-2)

Telapristone acetate, also known as CDB-4124, acts as an investigational selective progesterone receptor modulator (SPRM) tested for treatment of progesterone s...