Afuresertib - CAS 1047644-62-1
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
Afuresertib
Catalog Number:
1047644-62-1
Synonyms:
GSK-2110183; GSK 2110183; GSK2110183; GSK-2110183B; GSK 2110183B; GSK2110183B; Afuresertib.
CAS Number:
1047644-62-1
Description:
Afuresertib, also known as GSK2110183,  is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.
COA:
Inquire
MSDS:
Inquire
Targets:
Akt
Current Developer:
GlaxoSmithKline.
Chemical Structure
CAS 1047644-62-1 Afuresertib

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