AFP-464 - CAS 468719-52-0
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
AFP-464
Catalog Number:
468719-52-0
Synonyms:
AFP464.
CAS Number:
468719-52-0
Description:
AFP-464 is a synthetic lysyl prodrug of the amino-substituted flavone derivate aminoflavone with antiproliferative and antineoplastic activities. AFP464 is rapidly converted to aminoflavone in plasma. Aminoflavone activates the aryl hydrocarbon receptor (AhR) signaling pathway leading to an increase in cytochrome P450 1A1 (CYP1A1) and cytochrome P450 1A2 (CYP1A2) expression and, to a lesser extent, an increase in cytochrome P450 1B1 (CYP1B1) expression.
COA:
Inquire
MSDS:
Inquire
Current Developer:
Tigris Pharmaceuticals, Inc/ Kirax Corp.
Chemical Structure
CAS 468719-52-0 AFP-464