Afobazole hydrochloride - CAS 173352-39-1
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
Afobazole hydrochloride
Catalog Number:
173352-39-1
Synonyms:
CM346 hydrochloride; Afobazol hydrochloride; Fabomotizole hydrochloride; CM 346 hydrochloride; CM-346 hydrochloride
CAS Number:
173352-39-1
Description:
Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties.
Molecular Weight:
343.87
Molecular Formula:
C15H22ClN3O2S
COA:
Inquire
MSDS:
Inquire
Targets:
Others
Chemical Structure
CAS 173352-39-1 Afobazole hydrochloride

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