AFN-1252 - CAS 620175-39-5
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
AFN-1252
Catalog Number:
620175-39-5
Synonyms:
(E)-N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-3-yl)prop-2-enamide;
CAS Number:
620175-39-5
Description:
AFN-1252 is an enoyl-(acyl-carrier protein) reductase fabl inhibitor, inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml.
Molecular Weight:
375.43
Molecular Formula:
C22H21N3O3
Quantity:
Milligrams-Grams
Quality Standard:
Enterprise Standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
CC1=C(OC2=CC=CC=C12)CN(C)C(=O)C=CC3=CC4=C(NC(=O)CC4)N=C3
InChI:
1S/C22H21N3O3/c1-14-17-5-3-4-6-18(17)28-19(14)13-25(2)21(27)10-7-15-11-16-8-9-20(26)24-22(16)23-12-15/h3-7,10-12H,8-9,13H2,1-2H3,(H,23,24,26)/b10-7+
InChIKey:
QXTWSUQCXCWEHF-JXMROGBWSA-N
Targets:
Antibacterial
Current Developer:
Debiopharm Group

Related Antibacterial Products


CAS 1257426-19-9 TBA-354

TBA-354
(CAS: 1257426-19-9)

TBA-354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamani...

CAS 61379-65-5 Rifapentine

Rifapentine
(CAS: 61379-65-5)

Rifapentine (Priftin) is an semi-synthetic antibiotic compound used in the treatment of tuberculosis.

CAS 34604-60-9 5-hydroxypyrazine-2-carboxylic acid

5-hydroxypyrazine-2-carboxylic acid
(CAS: 34604-60-9)

A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide.

CAS 86-42-0 AMODIAQUINE

AMODIAQUINE
(CAS: 86-42-0)

Amodiaquine is a drug which used to treat malaria, including Plasmodium falciparum malaria when uncomplicated. It has similar action to chloroquine. It is not a...

CAS 32986-56-4 Tobramycin

Tobramycin
(CAS: 32986-56-4)

Tobramycin is an aminoglycoside antibiotic with an IC50 of 9.7 μM.

CAS 153-61-7 Cephalothin

Cephalothin
(CAS: 153-61-7)

Cephalothin, one of the first generation cephalosporin antibiotic, has been found to be probably effective in some respiratory diseases and neuromuscular juncti...

CAS 1405-37-4 Capreomycin Sulfate

Capreomycin Sulfate
(CAS: 1405-37-4)

Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.

CAS 102-65-8 Sulfaclozine

Sulfaclozine
(CAS: 102-65-8)

Sulfaclozine, a sulfonamide derivative, is a potent antibacterial and anticoccidial agent which is commonly used as a veterinary drug.

CAS 121123-17-9 Cefprozil monohydrate

Cefprozil monohydrate
(CAS: 121123-17-9)

Cefprozil hydrate (Cefzil) is a second-generation cephalosporin type antibiotic. Cefprozil hydrate (Cefzil) can be used to treat bronchitis, ear infections, ski...

CAS 74610-55-2 Tylosin tartrate

Tylosin tartrate
(CAS: 74610-55-2)

Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.

CAS 217500-96-4 Tulathromycin A

Tulathromycin A
(CAS: 217500-96-4)

Triamilide antibiotic for treatment of bovine and porcine respiratory disease. Exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and...

CAS 98-96-4 Pyrazinamide

Pyrazinamide
(CAS: 98-96-4)

Pyrazinamide is a pyrazine that is used therapeutically as an antitubercular agent. It is a prodrug that stops the growth of Mycobacterium tuberculosis. It was ...

CAS 87239-81-4 Cefpodoxime Proxetil

Cefpodoxime Proxetil
(CAS: 87239-81-4)

Cefpodoxime Proxetil is a third generation cephalosporin, ester prodrug of the active free acid metabolite Cefpodoxime. Cefpodoxime is active against most Gram-...

CAS 13614-98-7 Minocycline Hydrochloride

Minocycline Hydrochloride
(CAS: 13614-98-7)

Minocycline Hydrochlorideis the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA t...

CAS 50972-17-3 Bacampicillin

Bacampicillin
(CAS: 50972-17-3)

Bacampicillin may increase the anticoagulant activities of Acenocoumarol as a prodrug of ampicillin.

Oritavancin diphosphate
(CAS: 192564-14-0)

Oritavancin, also known as LY333328, is a novel semisynthetic glycopeptide antibiotics.Oritavancin possesses potent and rapid bactericidal activity in vitro aga...

CAS 773-76-2 Chloroxine

Chloroxine
(CAS: 773-76-2)

Chloroxine has bacteriostatic, fungistatic and antiprotozoal properties. It is effective against Streptococci, Staphylococci, Candida, Candida albicans, Shigell...

CAS 121577-32-0 Gatifloxacin hydrochloride

Gatifloxacin hydrochloride
(CAS: 121577-32-0)

Gatifloxacin (hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV...

CAS 1192491-61-4 Avibactam Sodium Salt

Avibactam Sodium Salt
(CAS: 1192491-61-4)

Avibactam Sodium Salt, a novel non-ᵦ-lactam ᵦ-lactamase inhibitor, binds covalently to Ambler class A ᵦ-lactamases, including KPCs, Ambler class C and some clas...

CAS 63-74-1 Sulfanilamide

Sulfanilamide
(CAS: 63-74-1)

Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.