AEZS-112 - CAS 1214741-69-1
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
AEZS-112
Catalog Number:
1214741-69-1
Synonyms:
ZEN012; ZEN 012; ZEN-012; AEZS 112; AEZS112.
CAS Number:
1214741-69-1
Description:
AEZS-112, also known as ZEN012, is an orally active small mol. anti-cancer drug which inhibits the polymn. of tubulin at low micromolar concns. AEZS 112 dose-dependently increased non-vital hypodiploid cells and the cytotoxic effect was least pronounced in G2 phase of the cell cycle. AEZS 112 showed anti-tumor activity in human ovarian and endometrial cancer cell lines at low micromolar concns., which could not be abrogated by caspase inhibition and is therefore a good candidate for in vivo studies in these tumors.
COA:
Inquire
MSDS:
Inquire
Current Developer:
AEterna Zentaris Inc.