AEZS-108 - CAS 139570-93-7
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
AEZS-108
Catalog Number:
139570-93-7
Synonyms:
AEZS 108; AEZS108; AN 152; AN-152; AN152; doxorubicin-GNRH agonist conjugate AEZS-108; doxorubicin-LHRH agonist conjugate AEZS-108. Zoptarelin Doxorubicin.
CAS Number:
139570-93-7
Description:
AEZS-108, also known as AN-152 or zoptarelin doxorubicin,  is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R). Zoptarelin doxorubicin binds to GnRH-1Rs, which may be highly expressed on endometrial and ovarian tumor cell membrane surfaces, and is internalized. Once inside the cell, the doxorubicin moiety of this agent intercalates into DNA and inhibits the topoisomerase II activity, which may result in the inhibition of tumor cell DNA replication and tumor cell proliferation.
COA:
Inquire
MSDS:
Inquire
Current Developer:
AEterna-Zentaris
Chemical Structure
CAS 139570-93-7 AEZS-108