ADX88178 - CAS 1235318-89-4
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
ADX88178
Catalog Number:
1235318-89-4
Synonyms:
SCHEMBL369060; GTPL6238; 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine
CAS Number:
1235318-89-4
Description:
This active molecular is a selectiveMetabotropic glutamate receptor 4 agonist and modulator under the development of Addex Therapeutics. In the marble burying test, ADX88178 can reduce the number of buried marbles Meanwhile, in the EPM (elevated plus maze) test, it can also increase open-arm exploration, indicative of anxiolytic-like efficacy. Now, preclinical trials for Anxiety disorders, Cocaine abuse, Multiple sclerosis and Parkinson's diseas were on-going.
Molecular Weight:
272.33
Molecular Formula:
C12H12N6S
Quantity:
Milligrams-Grams
Quality Standard:
In-house standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
CC1=NC(=NC=C1)NC2=NC(=C(S2)C)C3=CNN=C3
InChI:
InChI=1S/C12H12N6S/c1-7-3-4-13-11(16-7)18-12-17-10(8(2)19-12)9-5-14-15-6-9/h3-6H,1-2H3,(H,14,15)(H,13,16,17,18)
InChIKey:
MIQNXKWDQRNHAU-UHFFFAOYSA-N
Targets:
Metabotropic Glutamate Receptor 4
Current Developer:
Addex Therapeutics

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ADX88178
(CAS: 1235318-89-4)

This active molecular is a selectiveMetabotropic glutamate receptor 4 agonist and modulator under the development of Addex Therapeutics. In the marble burying t...