|Description||Adozelesin is an experimental antitumor drug of the duocarmycin class. It is the first of a class of DNA-sequence-selective alkylating agents. It binds to and alkylates DNA, resulting in a reduction of both cellular and simian virus 40 (SV40) DNA replication which ultimately reduces the rate of cancer growth. It has marginal efficacy in the treatment of metastatic breast cancer at the dosage and schedule used in clinic phase 1 and 2 trials. It was developed by Pharmacia and was terminated in clinic phase 2 trials.|
|Quality Standard||In-house standard|
|Current Developer||Adozelesin was developed by Pharmacia and was terminated in clinic phase 2 trials.|
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