adipiplon - CAS 840486-93-3
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
adipiplon
Catalog Number:
840486-93-3
Synonyms:
NG-273;7-((2-(3-fluoropyridin-2-yl)-1H-imidazol-1-yl)methyl)-2-methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidine
CAS Number:
840486-93-3
Description:
Adipiplon is GABAA receptor partial agonist. It can bind to the α3 subtype. Adipiplon is one of the first drugs selected for clinical development which is able to discriminate between α2 and α3, as well as showing little affinity for the α1 or α5 subtypes .Adipiplon is being researched as a potential medication for the treatment of anxiety and insomnia, and in 2008 it was being used in Phase IIb trials. But these trials were suspended after next-day side effects were discovered.
Molecular Weight:
351.39
Molecular Formula:
C18H18FN7
Quantity:
Milligrams-Grams
Quality Standard:
In-house standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
CCCC1=C(N=CN2C1=NC(=N2)C)CN3C=CN=C3C4=C(C=CC=N4)F
InChI:
InChI=1S/C18H18FN7/c1-3-5-13-15(22-11-26-17(13)23-12(2)24-26)10-25-9-8-21-18(25)16-14(19)6-4-7-20-16/h4,6-9,11H,3,5,10H2,1-2H3
InChIKey:
UAMAIHOEGLEXSV-UHFFFAOYSA-N
Targets:
GABA Receptor
Current Developer:
Ligand Pharmaceuticals
Chemical Structure
CAS 840486-93-3 adipiplon

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