Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be h...
A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.
Synthetic, a weak AChR antagonist.
Carothane complex ester , from plants of the Umbelliferae family.
Hydrobromide salt of (+)-Lappaconitine, a potential antitumor agent agent that induces HL-60 differentiation and apoptosis with analgesic activity as well.
Synthetic organophosphorous compound, a non-competitive GABA antagonist; potent convulsant: causes epileptoform seizures.
TTX is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels, blocking nerve and...
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Cloflubicyne is a potent non-competitive GABA antagonist, convulsant, laboratory insecticide.
Notexin exerts both presynaptic (blocks the release of acetylcholine) and myotoxic<br/>activities
Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other ...
Extracted from Korolkowia sewrtzowii. Potent antiarrhythmic (class I) belonging to a novel structural class.
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influen...
Protopine is a benzylisoquinoline alkaloid occurring in opium poppy, Corydalis tubers and other plants of the family papaveraceae, like Fumaria officinalis. It ...
Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Alkaloid, extracted from Thalictrum isopyroide.
Calicheamicin is a potent DNA-binding cytotoxic antibiotic.Calicheamicin being the most notable enediyne antitumor antibiotics derived from the bacterium Microm...
α-Neurotoxins from snake venoms that tightly bind nAChRs contain 60-75 amino acid (aa) residues and are linked by 4-5 disulfide bridges. an antagonist of the ni...