ACY-738 - CAS 1375465-91-0
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
ACY-738
Catalog Number:
1375465-91-0
Synonyms:
ACY-738; ACY 738; ACY738.
CAS Number:
1375465-91-0
Description:
ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.
Molecular Weight:
270.29
Molecular Formula:
C14H14N4O2
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
O=C(C1=CN=C(NC2(C3=CC=CC=C3)CC2)N=C1)NO
Targets:
HDAC

Related HDAC Products


CAS 864814-88-0 Resminostat

Resminostat
(CAS: 864814-88-0)

Resminostat is an orally bioavailable inhibitor of histone deacetylases (HDACs) with potential antineoplastic activity. Resminostat binds to and inhibits HDACs ...

CAS 726169-73-9 Mocetinostat

Mocetinostat
(CAS: 726169-73-9)

Mocetinostat is a rationally designed, orally available, Class 1-selective, small molecule, 2-aminobenzamide HDAC inhibitor with potential antineoplastic activi...

CAS 875320-29-9 Quisinostat

Quisinostat
(CAS: 875320-29-9)

Quisinostat, also known as JNJ-26481585, is an orally bioavailable, second-generation, hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potent...

CAS 1186222-89-8 4SC-202

4SC-202
(CAS: 1186222-89-8)

4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic act...

CAS 852475-26-4 MC1568

MC1568
(CAS: 852475-26-4)

UF010
(CAS: 537672-41-6)

UF-010 is a Class I HDAC inhibitor, inhibiting proliferation of a range of cancer cell lines.

CAS 1215493-56-3 RG2833

RG2833
(CAS: 1215493-56-3)

RGFP 109 is a histone deacetylase (HDAC) inhibitor that has shown to reverse FXN gene silencing in short-term studies of Friedreich ataxia (FRDA) patient cells.

CAS 20554-84-1 (-)-Parthenolide

(-)-Parthenolide
(CAS: 20554-84-1)

(-)-Parthenolide is a sesquiterpene lactone which occurs naturally in the plant feverfew(Tanacetum parthenium) and also promotes the ubiquitination of MDM2 and ...

CAS 1252003-15-8 Tubastatin A

Tubastatin A
(CAS: 1252003-15-8)

Tubastatin A is selective at all isozymes except HDAC8 and maintains over 1000-fold selectivity against all isoforms excluding HDAC8, where it has approximately...

ST7612AA1
(CAS: 1428535-92-5)

ST7612AA1 is a potent Histone deacetylase (HDCA) inhibitor. It showed an in vitro activity in the nanomolar range associated with a remarkable in vivo antitumor...

CAS 497833-27-9 Givinostat

Givinostat
(CAS: 497833-27-9)

Givinostat (INN) or gavinostat, aslo known as ITF2357,  is a histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic...

CAS 1012054-59-9 CUDC-101

CUDC-101
(CAS: 1012054-59-9)

CUDC-101 is a multi-targeted, small-molecule inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor tyrosine kinase (EGFR/ErbB1), and human e...

CAS 251456-60-7 M344

M344
(CAS: 251456-60-7)

M344 is a potent HDAC inhibitor, which can also induced expression of the pro-apoptotic genes, Puma and Bax, together with the morphological features of apoptos...

CAS 254964-60-8 Tasquinimod

Tasquinimod
(CAS: 254964-60-8)

Tasquinimod is a quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease b...

CAS 1045792-66-2 CAY10603

CAY10603
(CAS: 1045792-66-2)

CAY10603 is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM, as compared with 271, 252, 0.42, 6851, and 90.7 nM for HDAC1, 2, 3, 8, and 10, respecti...

CAS 1316214-52-4 Rocilinostat

Rocilinostat
(CAS: 1316214-52-4)

Rocilinostat, previously known as ACY-1215, is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activi...

ACY-738
(CAS: 1375465-91-0)

ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60...

CAS 58880-19-6 Trichostatin A

Trichostatin A
(CAS: 58880-19-6)

Trichostatin A, also known as TSA, is a HDAC inhibitor. TSA inhibits the eukaryotic cell cycle during the beginning of the growth stage. TSA can be used to alte...

CAS 404950-80-7 Panobinostat

Panobinostat
(CAS: 404950-80-7)

Panobinostat is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), induci...

HDAC-IN-2
(CAS: 1316215-12-9)

HDAC-IN-2, a selective HDAC inhibitor, has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis...