ACT-281959 - CAS 1159501-31-1
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
ACT-281959
Catalog Number:
1159501-31-1
Synonyms:
butyl 4-((R)-3-(bis(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)-2-(6-((S)-3-methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carboxamido)propanoyl)piperazine-1-carboxylate
CAS Number:
1159501-31-1
Description:
This molecular is a prodrug of ACT-246475 which is a selective P2Y12 receptor antagonist with a wider therapeutic window in the rat model. ACT-281959 is the phosphate of ACT-246475 and showed antithrombotic efficacy after oral administration in the rat ferric chloride model. In May 2016, Phase-I development is ongoing in France.
Molecular Weight:
850.86
Molecular Formula:
C38H55N6O14P
Quantity:
Milligrams-Grams
Quality Standard:
In-house standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
O=C(N1CCN(C([C@@H](NC(C2=NC(C3=CC=CC=C3)=NC(N4CC[C@@H](C4)OC)=C2)=O)CP(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)=O)CC1)OCCCC
Targets:
Others
Current Developer:
Originator:Actelion Pharmaceuticals

Related Products


ML281
(CAS: 1404437-62-2)

ML281, a quinoxalin derivative, has been found to be a STK33 inhibitor and could have probable effect against KRAS-dependent cancers. IC50: 14 nM.

CAS 478336-92-4 ISO-1

ISO-1
(CAS: 478336-92-4)

ISO-1 is an inhibitor of the dopachrome tautomerase activity of MIF. It blocks the activation of NF-κB and TNF-α secretion from LPS-treated macrophages and impr...

CAS 1083-57-4 Bucetin

Bucetin
(CAS: 1083-57-4)

Bucetin, a phenacetin analog, has antipyretic and analgesic effect. It has been discontinued for showing renal toxicity.

CAS 30652-11-0 Deferiprone

Deferiprone
(CAS: 30652-11-0)

A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transf...

CAS 1493694-70-4 UNC2250

UNC2250
(CAS: 1493694-70-4)

UNC2250 is a potent and selective Mer Kinase inhibitor. When applied to live cells, UNC2250 inhibited steady-state phosphorylation of endogenous Mer with an IC5...

ABT-515
(CAS: 189328-52-7)

CAS 42017-89-0 Fenofibric acid

Fenofibric acid
(CAS: 42017-89-0)

Fenofibric acid is a lipid regulating agent available as delayed release capsules for oral administration.

CAS 84611-23-4 Erdosteine

Erdosteine
(CAS: 84611-23-4)

Erdosteine is a mucolytic which is used in treatment of excessive viscous mucus.

CAS 1867-73-8 N6-methyladenosine

N6-methyladenosine
(CAS: 1867-73-8)

N6-Methyladenosine is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast.

FW1256
(CAS: 117089-08-4)

Exogenous H2S, as we know, has anti-inflammatory effects both in macrophages and in animal models. FW1256 is a slow release H2S dononr and it is much more poten...

LY-79771
(CAS: 74248-95-6)

LY-79771 is a antiobesity agent. It can be effective in preventing fat regain following energy deprivation.

CAS 28598-08-5 Cinoctramide

Cinoctramide
(CAS: 28598-08-5)

Cinoctramide is an intermediate of pharmaceutical synthesis.

RG7800
(CAS: 1449598-06-4)

RG7800 is a selective Survival of motor neuron 1 protein (SMN1) stimulant and Survival of motor neuron 2 protein (SMN2) modulator originated by Roche. RG7800 sh...

ATR-101 HCl
(CAS: 133825-81-7)

ATR-101 is a selective Acetyl CoA C-acetyltransferase inhibitor. ATR-101 is uniquely distributed to adrenal tissues and inhibition of adrenal ACAT1 by ATR-101 d...

AM-2159
(CAS: 83654-06-2)

AM-2159 is a bio-active chemical, but no detailed information has been published yet.

CAS 107668-79-1 Bulleyaconitine A

Bulleyaconitine A
(CAS: 107668-79-1)

Bulleyaconitine A, an active indegrent from aconitum bulleyanum Diel, has been found to be effective in the treatment of chronic pain and rheumatoid arthritis.

CAS 84782-21-8 Cgp 8716

Cgp 8716
(CAS: 84782-21-8)

Cgp 8716 is a major metabolite of GP53,633 which is a basic non-steroidal anti-inflammatory agent Originated by Novartis.

20-O-Acetylingenol-3-angelate
(CAS: 82425-35-2)

20-O-Acetylingenol-3-angelate is a natural compound extracted from Euphorbia conspicua N. E. Br. It is used as molluscicidal agent, anti-cancer agent and cytost...

LY 255262
(CAS: 124986-45-4)

This bio-active molecular is a antibacterial agent with a pyrazolidinone structure.

CAS 138-41-0 Carzenide

Carzenide
(CAS: 138-41-0)

Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors.