|Description||Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion ofVLDL cholesterol, which leads indirectly to a modest reduction in LDL and increase in HDL cholesterol.|
RSM-932A is a novel anticancer drug. Its target is the human choline kinase alpha. Choline kinase alpha is an enzyme involved in increased lipid metabolism of c...
CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma.
Doxorubicin-SMCC, a derivative of doxorubicin with a SMCC linker, can react with sulfhydryl groups at pH 6.5-7.5 to form a stable thioether bond. Doxorubicin-SM...
Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors.
Dibenzothiophene (DBT) is a model compound for organic sulfur in fossil fuels.
Eslicarbazepine acetate, (BIA 2-093), is a promising antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine.
PD-138312 is a novel broad-spectrum 7-pyrrolidinyl fluoronaphthyridines with a difluorophenyl substitution or a cyclopropyl at the 1 positions, respectively. It...
Pamidronic acid (INN) or pamidronate disodium (USAN), pamidronate disodium pentahydrate is a nitrogen-containingbisphosphonate, used to prevent osteoporosis.
Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.
Miglustat is an inhibitor of the ceramide-specific glycosyltransferase, which catalyzes the first step of glycosphingolipid biosynthesis and is currently approv...
Created by the enzyme protoporphyrinogen oxidase, protoporphyrin IX is an important precursor to biologically essential prosthetic groups.
Ginsenoside Rg1, the predominant ginsenoside in the rhizome,shows no hemolytic nor cytotoxic activities.It acts as a weak phytoestrogen, presumably by binding a...
Daidzin is a natural organic compound in the class of phytochemicals known as isoflavones.Daidzin has shown the potential for the treatment of alcohol dependenc...
Elamipretide is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide under the development of Stealth BioTherapeutics. It can Improve left Vent...
FE-999024, a dipeptide compound, has been found to be a kallikrein inhibitor that was once studied in pancreatitis by Ferring Pharmaceuticals.
Artemotil is a fast acting blood schizonticide. It is a semi-synthetic derivative of artemisinin, which is a natural product of the Chinese plant Artemisia annu...
Bergenin is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid.It shows a potent immunomodulatory effect.
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM.
Metaxalone is a muscle relaxant. The mechanism of action of metaxalone in humans is not fully understood. It was suggested that it acts through general central ...
Sulfacarbamide is an antibiotic acting on the vegetative nervous system.