Acesulfame Potassium - CAS 55589-62-3
Not Intended for Therapeutic Use. For research use only.
Product Name:
Acesulfame Potassium
Catalog Number:
CAS Number:
Acesulfame potassium is a non-nutritive sweetener.
Molecular Weight:
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Chemical Structure
CAS 55589-62-3 Acesulfame Potassium

Reference Reading

1.Ion-exchange molecularly imprinted polymer for the extraction of negatively charged acesulfame from wastewater samples.
Zarejousheghani M1, Schrader S2, Möder M2, Lorenz P3, Borsdorf H4. J Chromatogr A. 2015 Sep 11;1411:23-33. doi: 10.1016/j.chroma.2015.07.107. Epub 2015 Aug 1.
Acesulfame is a known indicator that is used to identify the introduction of domestic wastewater into water systems. It is negatively charged and highly water-soluble at environmental pH values. In this study, a molecularly imprinted polymer (MIP) was synthesized for negatively charged acesulfame and successfully applied for the selective solid phase extraction (SPE) of acesulfame from influent and effluent wastewater samples. (Vinylbenzyl)trimethylammonium chloride (VBTA) was used as a novel phase transfer reagent, which enhanced the solubility of negatively charged acesulfame in the organic solvent (porogen) and served as a functional monomer in MIP synthesis. Different molecularly imprinted polymers were synthesized to optimize the extraction capability of acesulfame. The different materials were evaluated using equilibrium rebinding experiments, selectivity experiments and scanning electron microscopy (SEM). The most efficient MIP was used in a molecularly imprinted-solid phase extraction (MISPE) protocol to extract acesulfame from wastewater samples.
2.[Association between non-nutritive sweeteners and obesity risk among university students in Latin America].
Durán Agúero S, Blanco Batten E, Rodríguez Noel Mdel P, Cordón Arrivillaga K, Salazar de Ariza J, Record Cornwall J, Cereceda Bujaico Mdel P, Antezana Almorza S, Espinoza Bernardo S, Encina Vega C. Rev Med Chil. 2015 Mar;143(3):367-73. doi: 10.4067/S0034-98872015000300012.
BACKGROUND: The association between non-nutritive sweeteners and obesity is controversial.
3.Sources of aminomethylphosphonic acid (AMPA) in urban and rural catchments in Ontario, Canada: Glyphosate or phosphonates in wastewater?
Struger J1, Van Stempvoort DR2, Brown SJ2. Environ Pollut. 2015 Sep;204:289-97. doi: 10.1016/j.envpol.2015.03.038. Epub 2015 May 24.
Correlation analysis suggests that occurrences of AMPA in streams of southern Ontario are linked mainly to glyphosate in both urban and rural settings, rather than to wastewater sources, as some previous studies have suggested. For this analysis the artificial sweetener acesulfame was analyzed as a wastewater indicator in surface water samples collected from urban and rural settings in southern Ontario, Canada. This interpretation is supported by the concurrence of seasonal fluctuations of glyphosate and AMPA concentrations. Herbicide applications in larger urban centres and along major transportation corridors appear to be important sources of glyphosate and AMPA in surface water, in addition to uses of this herbicide in rural and mixed use areas. Fluctuations in concentrations of acesulfame and glyphosate residues were found to be related to hydrologic events.
4.Artificial sweeteners: safe or unsafe?
Qurrat-ul-Ain, Khan SA. J Pak Med Assoc. 2015 Feb;65(2):225-7.
Artificial sweeteners or intense sweeteners are sugar substitutes that are used as an alternative to table sugar. They are many times sweeter than natural sugar and as they contain no calories, they may be used to control weight and obesity. Extensive scientific research has demonstrated the safety of the six low-calorie sweeteners currently approved for use in foods in the U.S. and Europe (stevia, acesulfame-K, aspartame, neotame, saccharin and sucralose), if taken in acceptable quantities daily. There is some ongoing debate over whether artificial sweetener usage poses a health threat .This review article aims to cover thehealth benefits, and risks, of consuming artificial sweeteners, and discusses natural sweeteners which can be used as alternatives.