|Description||Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. It works by blocking the action of a substance in the body called cyclo-oxygenase.|
A highly selective COX-2 inhibitor
BMS-347070 is a COX-2 inhibitor, initially developed for the treatment for Colorectal cancer.
Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. It is a n...
An inhibitor of COX-1 and COX-2
An inhibitor of COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively
A COX-2 inhibitor with IC50 of 0.2 μM
A selective COX-2 inhibitor
Dexibuprofen is a Cyclooxygenase inhibitor originated by Gebro Pharma GmbH. It is a non-steroidal anti-inflammatory drug as the active dextrorotatory enantiomer...
A nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively
This active molecular is a Leukotriene B4 antagonist. PD- 127443 is also a 5-lipoxygenase and cyclooxygenase inhibitor and it has been reported to have antiinfl...
Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects.
Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
SC-560 is an orally active and highly selective cyclooxygenase-1 (COX-1) inhibitor with IC50= 0.009 μM for COX-1, and 6.3 μM for COX-2. SC-560 also significantl...
Phenacetin is a non-opioid analgesic without anti-inflammatory properties. It is a pain-relieving and fever-reducing drug and was withdrawn from the Canadian ma...
Harpagoside, isolated from the Harpagophytum procumbens (Devil's Claw) root or Crophularia ningpoensis Hemsl (Figwort), inhibited lipopolysaccharide-induced mRN...
Ketorolac, a non-selective COX inhibitor, is a non-steroidal anti-inflammatory drug. It shows inhibition of eicosanoid formation in HEL cells (COX-1) and LPS-st...
A salicylate and irreversible COX1 and COX2 inhibitor
Naproxcinod, a nitro compound, has been found to be a nitric oxide donor as well as a cyclooxygenase inhibitor that was once studied aginast duchenne muscular d...
Flumizole is a non-steroidal anti-inflammatory drug (NSAID) that acts via inhibition of the enzyme cyclooxygenase (COX).