Acalisib - CAS 870281-34-8
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
Acalisib
Catalog Number:
870281-34-8
Synonyms:
GS-9820; GS9820; GS 9820; CAL-120; CAL 120; CAL120; Acalisib; UNII-OVW60IDW1D.
CAS Number:
870281-34-8
Description:
Acalisib, also known as GS-9820,  is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide-3 kinases (PI3K) with potential immunomodulating and antineoplastic activities. p110beta/delta PI3K inhibitor GS-9820 inhibits the activity of PI3K, thereby preventing the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3), which decreases tumor cell proliferation and induces cell death. PI3K-mediated signaling is often dysregulated in cancer cells; the targeted inhibition of PI3K is designed to preserve PI3K signaling in normal, non-neoplastic cells.
COA:
Inquire
MSDS:
Inquire
Targets:
PI3K
Current Developer:
Gilead Sciences
Chemical Structure
CAS 870281-34-8 Acalisib

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