AC410 - CAS 1361415-84-0
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
AC410
Catalog Number:
1361415-84-0
Synonyms:
(S)-(4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol;1361415-86-2 (HCl)
CAS Number:
1361415-84-0
Description:
AC410 is a Janus kinase 2 (JAK2) inhibitor with Kd of 0.18 nM. AC410 is selective for JAK2 and Kd is 2.5 nM for JAK1 and 5nM for JAK3. Phase I for the treatment of Autoimmune disorders and Inflammation is on-going.
Molecular Weight:
349.40
Molecular Formula:
C19H16FN5O
Quantity:
Milligrams-Grams
Quality Standard:
In-house standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
O[C@@H](C1=CC=C(F)C=C1)C2=NC(NC3=NNC(C)=C3)=C4C=CC=CC4=N2
Targets:
JAK
Current Developer:
Daiichi Sankyo Company

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