ABT724 - CAS 70006-24-5
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
ABT724
Catalog Number:
70006-24-5
Synonyms:
2-((4-Pyridin-2-ylpiperazine-1-yl)methyl)-1H-benzimidazole;587870-77-7(ABT 724 trihydrochloride)
CAS Number:
70006-24-5
Description:
ABT-724 is a dopamine D4 agonist originated by Abbott Laboratories with EC50 value of 12.4 nM. In Dec 2007, Phase-II for Erectile dysfunction was discontinued in USA. Now ABT-724 continues to be used in scientific research into the function of the D4 receptor.
Molecular Weight:
293.37
Molecular Formula:
C17H19N5
Quantity:
Milligrams-Grams
Quality Standard:
In-house standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
c1ccc2c(c1)[nH]c(n2)CN3CCN(CC3)c4ccccn4
InChI:
1S/C17H19N5/c1-2-6-15-14(5-1)19-16(20-15)13-21-9-11-22(12-10-21)17-7-3-4-8-18-17/h1-8H,9-13H2,(H,19,20)
InChIKey:
FRPJGTNLZNXQEX-UHFFFAOYSA-N
Targets:
Dopamine Receptor
Current Developer:
Originator Abbott Laboratories
Chemical Structure
CAS 70006-24-5 ABT724

Related Dopamine Receptor Products


ML398 hydrochloride
(CAS: 1379510-21-0)

ML398 is potent dopamine 4 receptor antagonist with IC50 value of 130 nM and Ki of 36 nM. It exhibits no activity against the other dopamine receptors tested (>...

(±)-Methotrimeprazine D6
(CAS: 1189805-51-3)

The isotope labelled form of (±)-Methotrimeprazine which is an antagonist of D3 dopamine and Histamine H1 receptor and the (R)- isomer form of it could be used ...

CAS 62717-42-4 SKF-38393 hydrochloride

SKF-38393 hydrochloride
(CAS: 62717-42-4)

SKF-38393, aslo known as (+/-)-SKF-38393, is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist. It...

Ecopipam
(CAS: 112108-01-7)

Ecopipam, a synthetic benzazepine derivative drug, acts as a selective dopamine D1/D5 receptor antagonist with little affinity for either dopamine D2-like or 5-...

CAS 138982-67-9 Ziprasidone hydrochloride monohydrate

Ziprasidone hydrochloride monohydrate
(CAS: 138982-67-9)

The hydrochloride monohydrate salt form of Ziprasidone, a benzothiazol derivative, has been found to be a 5HT2A and D2 receptor antagonist that could be used ag...

Amitifadine hydrochloride
(CAS: 410074-74-7)

A Serotonin-Preferring Triple Reuptake Inhibitor for the Treatment of Major Depression, with the IC50 values for serotonin, norepinephrine and dopamine reuptake...

Iloperidone hydrochloride
(CAS: 1299470-39-5)

The hydrochloride salt form of Iloperidone which is a antagonist of both D2 and 5-HT2 receptor and has been commonly used against schizophrenia. IC50: 10-100 nm...

ABT670
(CAS: 630119-43-6)

ABT670 is a drug which acts as a potent, superior orally bioavailable dopamine agonist selective for the D4 subtype. It was used as a possible treatment for ere...

CAS 101626-70-4 TALIPEXOLE

TALIPEXOLE
(CAS: 101626-70-4)

Talipexole (B-HT920) is a highly selective agonist of D2 receptor and α2-adrenoceptor which has better ameliorative rate of symptom than bromocriptine and might...

CAS 23672-07-3 Levosulpiride

Levosulpiride
(CAS: 23672-07-3)

Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.Levosulpiride is used in the treatment of psycho...

CAS 146-54-3 Triflupromazine

Triflupromazine
(CAS: 146-54-3)

Triflupromazine, a phenothiazin derivative, has been found to be a D2 dopamine receptor antagonist that could probably used as a tranquilizer and antipsychotic ...

CAS 34161-24-5 Fipexide hydrochloride

Fipexide hydrochloride
(CAS: 34161-24-5)

Fipexide hydrochloride is a nootropic agent that displays a positive effect on cognitive function

NS-2359
(CAS: 195875-68-4)

NS-2359, a serotonin-norepinephrine-dopamine reuptake inhibitor, may be able to reduce cocaine withdrawal symptoms, reduce cocaine craving and reduce cocaine-in...

CAS 53583-79-2 Barnetil

Barnetil
(CAS: 53583-79-2)

Barnetil acts as a selective D2 and D3 receptor antagonist, which has high affinity for these receptors of dissociation constants of 2.2 nM and 2.4 nM respectiv...

JPC-211
(CAS: 82668-33-5)

JPC-211 is a selective dopamine D3 receptor agonist.

CAS 122883-93-6 Ziprasidone Hydrochloride

Ziprasidone Hydrochloride
(CAS: 122883-93-6)

The hydrochloride salt form of Ziprasidone which is an antagonism of both serotonin and dopamine receptor and could be effective against schizophrenia.

CAS 327026-93-7 Lensiprazine

Lensiprazine
(CAS: 327026-93-7)

Lensiprazine is a potent in vitro dopamine receptor antagonist and highly active as serotonin reuptake inhibitor.

CAS 132810-10-7 Blonanserin

Blonanserin
(CAS: 132810-10-7)

A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic.

CAS 117-89-5 trifluoperazine

trifluoperazine
(CAS: 117-89-5)

Trifluoperazine is a typical antipsychotic of the phenothiazine chemical class with anti-adrenergic and anti-dopaminergic actions just similar to Chlorpromazine...

Brexpiprazole
(CAS: 913611-97-9)

Brexpiprazole, a novel atypical antipsychotic drug, is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). It is approved for the...