ABT 925 Fumerate - CAS 220519-07-3
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
ABT 925 Fumerate
Catalog Number:
220519-07-3
Synonyms:
(E)-but-2-enedioic acid;2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one; UNII-DMH23OL273; 220519-07-3 (anhydrous); 220519-06-2 (anhydrous free base); ABT-925 anhydrous
CAS Number:
220519-07-3
Description:
A 437203 is a selective dopamine (DA) D3 receptor antagonist suited to evaluate the physiological role(s) of D3 receptors. A 437203 shows an approximately 100-fold higher in vitro affinity for dopamine D₃ versus D₂ receptors.
Molecular Weight:
572.604
Molecular Formula:
C24H31F3N6O5S
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
CC(C)(C)C1=NC(=CC(=N1)N2CCN(CC2)CCCSC3=NC=CC(=O)N3)C(F)(F)F.C(=CC(=O)O)C(=O)O
InChI:
1S/C20H27F3N6OS.C4H4O4/c1-19(2,3)17-25-14(20(21,22)23)13-15(26-17)29-10-8-28(9-11-29)7-4-12-31-18-24-6-5-16(30)27-18;5-3(6)1-2-4(7)8/h5-6,13H,4,7-12H2,1-3H3,(H,24,27,30);1-2H,(H,5,6)(H,7,8)/b;2-1+
InChIKey:
KQMGYGQUUXCWBL-WLHGVMLRSA-N
Targets:
Dopamine Receptor

Related Dopamine Receptor Products


CAS 91374-20-8 Ropinirole HCl

Ropinirole HCl
(CAS: 91374-20-8)

Ropinirole a selective D-2 agonist with Ki of 29 nM.

CAS 53583-79-2 Barnetil

Barnetil
(CAS: 53583-79-2)

Barnetil acts as a selective D2 and D3 receptor antagonist, which has high affinity for these receptors of dissociation constants of 2.2 nM and 2.4 nM respectiv...

CAS 52-86-8 Haloperidol

Haloperidol
(CAS: 52-86-8)

Haloperidol (Haldol) is an antipsychotic and butyrophenone.

CAS 548-73-2 Droperidol

Droperidol
(CAS: 548-73-2)

Droperidol is a potent antagonist of dopamine subtype 2 receptors in the limbic system.

CAS 104632-27-1 Pramipexole impurity D

Pramipexole impurity D
(CAS: 104632-27-1)

The dihydrochloride salt form of dexpramipexole, also known as R-(+)-Pramipexole, is one of the impurities of pramipexole. It coule be used as a negative contro...

CAS 346688-38-8 Pridopidine

Pridopidine
(CAS: 346688-38-8)

Pridopidine, also known as ACR16, is a dopamine stabilizer used in the treatment of neurologic and psychiatric disorders.

CAS 524-83-4 Etybenzatropine

Etybenzatropine
(CAS: 524-83-4)

Etybenzatropine is an anticholinergic/antihistamine. It is used as an antiparkinsonian agent. It may act as a dopamine reuptake inhibitor.

CAS 146-56-5 Fluphenazine DiHCl

Fluphenazine DiHCl
(CAS: 146-56-5)

Fluphenazine DiHCl is the dihydrochloride salt preparation of Fluphenazine. It has been used to deliver Fluphenazine to biological systems in studies probing th...

CAS 34161-24-5 Fipexide hydrochloride

Fipexide hydrochloride
(CAS: 34161-24-5)

Fipexide hydrochloride is a nootropic agent that displays a positive effect on cognitive function

CAS 101626-70-4 TALIPEXOLE

TALIPEXOLE
(CAS: 101626-70-4)

Talipexole (B-HT920) is a highly selective agonist of D2 receptor and α2-adrenoceptor which has better ameliorative rate of symptom than bromocriptine and might...

CAS 125572-93-2 Rotigotine Hydrochloride

Rotigotine Hydrochloride
(CAS: 125572-93-2)

The hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's dise...

CAS 53-60-1 Promazine Hydrochloride

Promazine Hydrochloride
(CAS: 53-60-1)

Promazine Hydrochloride is a phenothiazine used in short-term treatment of disturbed behavior and as an antiemetic.

CAS 113-59-7 Chlorprothixene

Chlorprothixene
(CAS: 113-59-7)

Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM...

CAS 62717-42-4 SKF-38393 hydrochloride

SKF-38393 hydrochloride
(CAS: 62717-42-4)

SKF-38393, aslo known as (+/-)-SKF-38393, is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist. It...

1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4
(CAS: 74115-01-8)

1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1) is a synthetic compound belongs to the benzazepine class ....

CAS 132810-10-7 Blonanserin

Blonanserin
(CAS: 132810-10-7)

A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic.

CAS 215803-78-4 Sb-277011

Sb-277011
(CAS: 215803-78-4)

Sb-277011 is a novel, high-anity and selective dopamine D3 receptor antagonist that may have potential in treating the negative symptoms of schizophrenia. pKi:...

CAS 1841-19-6 Fluspirilene

Fluspirilene
(CAS: 1841-19-6)

Fluspirilene, with antipsychotic activity, is a non-competitive antagonist of agonist-activated L-type calcium channels (IC50 = 0.03 µM). Fluspirilene is also a...

CAS 136765-35-0 Haloperidol D4

Haloperidol D4
(CAS: 136765-35-0)

The isotope labelled forn of Haloperidol, a Dopamine receptor blocker, could be used against schizophrenia and other sorts of psychosis.

Adrogolide Hydrochloride
(CAS: 166591-11-3)

The hydrochloride salt form of Adrogolide,a quinoline derivative, has been found to be a dopamine D1 receptor agonist that was once studied in Parkinson's disea...