|Synonyms||N-[(2S)-1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-3-[4-[4-(trifluoromethoxy)phenyl]phenoxy]propan-2-yl]-N-hydroxyformamide; UNII-I8NWP25THF; CHEMBL40143; ABT-770|
|Description||ABT-770 is a selective and orally bioavailable MMP inhibitor.|
Batimastat (also known as BB-94) is a synthetic matrix metalloproteinase inhibitor that has shown antineoplastic and antiangiogenic activity in various tumor mo...
Marimastat is an orally-active synthetic broad spectrum inhibitor of MMPs (IC50 values are 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respec...
CP-544439 is a selective matrix metalloproteinase-13 inhibitor.
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. SB-3CT is a 2-[(arylsulfonyl)methyl]thiirane that achieves potent inhibition, by a thiira...
Ilomastat, also known as GM6001 and galardin, is a broad-spectrum matrix metalloproteinase inhibitor with potential anticancer activity. GM6001 is a member of t...
ARP 101 is a Selective MMP-2 inhibitor with IC50 value of 0.81 nM. It displays nearly 600-fold selectivity over MMP-1 (IC50 value 486 nM). ARP 101 has diverse p...
ABT-770 is a selective and orally bioavailable MMP inhibitor.
Batimastat sodium salt
Batimastat sodium salt (BB-94) is a potent, broad spectrum matrix metalloprotease (MMPs) inhibitor with IC50s of 3/4/20/6/4 nM for MMP-1/2/3/7/9 respectively.
CM-352 has been found to be a MMP inhibitor that could probably be used as an antihemorrhagic agent with little influence in normal hemostatic function.
CTS-1027 inhibits individual members of the MMP family that are believed to be important in inflammation and tissue damage. CTS-1027 was specifically designed, ...
CP 471474 a broad spectrum Matrix Metalloprotease inhibitor with sub-nanomolar affinity for MMP-2 and 13 among MMPs (IC50: 1170, 0.7, 16, 13, 0.9 for MMP-1, MM...