|Description||ABT-239 is a novel, highly efficacious, non-imidazole class of H3R antagonist has been investigated as a treatment for ADHD, Alzheimer's disease, and schizophrenia.|
|Quality Standard||Enterprise standard|
Histamine is an organic nitrogenous compound produced by basophils and by mast cells found in nearby connective tissues.
Bepotastine stimulates P-gp-mediated ATP hydrolysis with Km, Vmax, and Vmax/Km values of 1.25 mM, 108 nmol/min/mg protein, and 0.087 mL/min/mg protein, respecti...
Fexofenadine is Histamine H1 receptor antagonist. It can be used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria.
Chlorcyclizine is a first-generation Histamine Receptor antagonist of the phenylpiperazine class. It can be used primarily to treat allergy symptoms such as rhi...
Dimethindene is a selective histamine H1 antagonist. It binds to the histamine H1 receptor. It is an antiallergic drug and is used in hypersensitivity reactions...
Azelastine HCl is a potent, second-generation, selective, histamine antagonist.
JNJ-10191584 is a selective histamine H4 receptor antagonist. It inhibits mast cell in vitro with IC50 value of 138nM. JNJ-10191584 has antiinflammatory and ana...
Chlorphenoxamine is an analog of diphenhydramine. It has antimuscarinic and antihistaminic properties. It has been used as an antipruritic and antiparkinsonian ...
Cetirizine is a major metabolite of hydroxyzine, and a racemic selective H1 receptor antagonist.
Mianserin Hydrochloride is a psychoactive drug of the tetracyclic antidepressant.It is classified as a noradrenergic and specific serotonergic antidepressant (N...
Hydroxyzine pamoate, a derivative of hydroxyzine, is a histamine H1-receptor antagonist that has been used as anxiolytic and antihistaminic so that it is probab...
ABT-239 is a novel, highly efficacious, non-imidazole class of H3R antagonist has been investigated as a treatment for ADHD, Alzheimer's disease, and schizophr...
Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.
Ebrotidine(FI 3542), a competitive H2-receptor antagonist, has gastroprotective activity under the condition of gastric mucosal damage caused by some stress res...
OUP16 is a potent and selective histamine H4 receptor(hH4R) agonist with 40-fold selectivity over the hH3R and superior to its (2S,5S)-configured optical antipo...
Diphenylpyraline, a piperidine derivative, has been found to be a H1 receptor antagonist that could be probably effective against some allergy acts.
Hydroxyzine (sold as Vistaril, Atarax) is a first-generation antihistamine of the diphenylmethane and piperazine class.
Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.
Triprolidine hydrochloride is a potent H1 histamine receptor antagonist. It is used in allergic rhinitis, urticaria and asthma. It is an over-the-counter antihi...
Pyrilamine maleate salt
Pyrilamine maleate salt is a first generation antihistamine and binds with high affinity to G(q/11) protein. It is commonly utilized as a radioligand binding as...