ABT-199 - CAS 1257044-40-8
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
ABT-199
Catalog Number:
1257044-40-8
CAS Number:
1257044-40-8
COA:
Inquire
MSDS:
Inquire
Targets:
Bcl-2 Family
Chemical Structure
CAS 1257044-40-8 ABT-199

Related Bcl-2 Family Products


CAS 579492-81-2 Bax inhibitor peptide V5

Bax inhibitor peptide V5
(CAS: 579492-81-2)

Bax inhibitor peptide V5, a peptide inhibitor, as a pro-apoptotic member of Bcl-2 family proteins and plays an important role in mitochondria-dependent apoptosi...

Marinopyrrole A
(CAS: 1227962-62-0)

Marinopyrrole A, a new Mcl-1 inhibitor, could influence Mcl-1-Bim interaction and induce the degradation of Mcl-1 proteasomal and also lead to the apoptosis of ...

(+)-Apogossypol
(CAS: 66389-74-0)

(+)-Apogossypol is a potent inhibitor of Bcl-2 family proteins, binding and inhibiting Bcl-2 and Bcl-X(L) with high affinity and induces apoptosis of tumor cell...

CAS 1257044-40-8 ABT-199

ABT-199
(CAS: 1257044-40-8)

A-1155463
(CAS: 1235034-55-5)

A-1155463, an effective and selective BCL-XL inhibitor, has been studied to have probable effect in restraining the growth of small cell lung cancer xenograft t...

S63845
(CAS: 1799633-27-4)

S63845, a thienopyrimidine derivative, is a potent inhibitor that specifically binds with high affinity to the BH3-binding groove of a protein of the BCL2 famil...

CAS 518303-20-3 UMI-77

UMI-77
(CAS: 518303-20-3)

UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family.

CAS 331244-89-4 BAM7

BAM7
(CAS: 331244-89-4)

BAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM.

CAS 90141-22-3 AT101

AT101
(CAS: 90141-22-3)

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM.

Mcl1-IN-2
(CAS: 292057-76-2)

Mcl1-IN-2, a hydroxyquinoline derivative, is an Mcl-1 inhibitor.

(S)-Gossypol acetic acid
(CAS: 1189561-66-7)

(S)-Gossypol acetic acid, a Bcl-2 inhibitor, could effectively induce the death of Jurkat cells in which Bcl-2 or Bcl-xL is overexpressed. IC50: 18.1μM and 22.9...

WEHI-539
(CAS: 1431866-33-9)

WEHI-539, a selective BCL-XL inhibitor that can be function as a single-agent inducer of apoptosis while sparing normal cells, it leads to MOMP and apoptosis du...

CAS 2752-65-0 Gambogic acid

Gambogic acid
(CAS: 2752-65-0)

Gambogic acid is a natural product inhibitor of Hsp90.

Pyridoclax
(CAS: 1651890-44-6)

Pyridoclax, a pyridine derivative, has been found to be a Mcl-1 inhibitor that could induce apoptosis of cancer cells. IC50: 25 nM(Kd).

CAS 803712-79-0 Obatoclax

Obatoclax
(CAS: 803712-79-0)

Obatoclax mesylate is the mesylate salt of obatoclax, a synthetic small-molecule inhibitor of the bcl-2 family of proteins with potential pro-apoptotic and anti...

BDA 366
(CAS: 1821496-27-8)

BDA-366 is a BCL2-BH4 antagonist(Ki=3.3nM) which suppresses human myeloma growth. BDA-366 induces apoptosis in MM cell lines and primary MM cells by inducing BC...

CAS 12542-36-8 Gossypol Acetic Acid

Gossypol Acetic Acid
(CAS: 12542-36-8)

The Acetate acid salt form of gossypol which may represent a promising new anticancer agent with a novel molecular mechanism and warrants further investigation ...

CAS 303-45-7 Gossypol

Gossypol
(CAS: 303-45-7)

Gossypol is an orally-active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from unrefined cottonseed oil, gossypol induces cel...

Mcl1-IN-1
(CAS: 713492-66-1)

Mcl1-IN-1 is a potent Mcl-1-selective inhibitor with IC50 of 2.4 uM, relative to the related Bcl-2 family protein Bcl-xL.

CAS 852808-04-9 ABT-737

ABT-737
(CAS: 852808-04-9)