A66 - CAS 1166227-08-2
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
A66
Catalog Number:
1166227-08-2
Synonyms:
N/A
CAS Number:
1166227-08-2
Description:
Inhibition of p110α alone by A66 treatment is sufficient to block insulin signalling to Akt/PKB in certain cell lines that harbor H1047R mutations in PIK3CA and have high levels of p110α and class-Ia PI3K activity.
Molecular Weight:
393.53
Molecular Formula:
C17H23N5O2S2
COA:
Inquire
MSDS:
Inquire
Targets:
PI3K
Chemical Structure
CAS 1166227-08-2 A66

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Reference Reading


1.Draft Genome Sequence of the Streptococcus pneumoniae Avery Strain A66.
Hahn C1, Harrison EM2, Parkhill J3, Holmes MA2, Paterson GK4. Genome Announc. 2015 Jun 25;3(3). pii: e00697-15. doi: 10.1128/genomeA.00697-15.
We have used HiSeq 2000 technology to generate a draft genome sequence of Streptococcus pneumoniae strain A66. This is a common study strain used in investigations of pneumococcal bacterium-host interactions and was used in the seminal genetic studies of Avery et al.