|Product Name||A 438079 hydrochloride|
|Synonyms||3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride|
|Description||A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores.|
|Quality Standard||In-house standard|
This molecular is a piperidine derivative with an amine protecting group. It may be used in the preparation of biologically active compounds like selective irre...
Ropidoxuridine is a novel, orally available 5-substituted 2-pyrimidinone-2'-deoxyribonucleoside analogue and prodrug of 5-iododeoxyuridine (IUdR). It has radios...
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It plays a role in the activity of...
Propanil is a widely used contact herbicide mainly used to control weed growth in rice fields.
Anti-inflammatory agent. MAPK inhibitor. Inhibits p38, ERK and JNK phosphorylation. Inhibits NFκB activation. Shows antitussive, expectorant and anti-inflammato...
GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity.
Ligustrazine Hydrochloride is a natural product extracted from the rhizomes of Ligusticum chuanxiong Hort. It displayed a protection effect on injured ECV304 ce...
BVT 2733 is a non-steroidal small molecule as a a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM w).
Pamidronic acid (INN) or pamidronate disodium (USAN), pamidronate disodium pentahydrate is a nitrogen-containingbisphosphonate, used to prevent osteoporosis.
Atractylenolide III is a major component of Atractylodes rhizome, which can induce apoptosis of the lung carcinoma cells.
L-Arginine HCl (L-Arg)
L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
CC122 is a novel agent for DLBCL. It is an orally available pleiotropic pathway modulator. It has antitumor and immunomodulatory activity. It is used for the tr...
Oct4 is a transcription factor which is involved in the reprogramming of somatic cells to produce pluripotent stem cells.
Ginsenoside Rf, extracted from the traditional Chinese herb ginseng used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory ac...
Amidantel is a potent anthelminthic agent.
Ornipressin Acetate, an analogue of Vasopressin, is used as a vasoconstrict or haemostatic and renal agent.
Antiviral and antitumor agent.
Lactitol monohydrate is an analogue of disaccharide lactulose. lt is used as replacement sweeteners and has been used in the treatment of constipation & hepatic...
Tiagabine hydrochloride is an anticonvulsant and selective GABA reuptake inhibitor through inhibition of the synaptic GABA transporter GAT1. Tiagabine increases...
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)