A 438079 hydrochloride - CAS 899507-36-9
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
A 438079 hydrochloride
Catalog Number:
899507-36-9
Synonyms:
3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride
CAS Number:
899507-36-9
Description:
A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores.
Molecular Weight:
342.61
Molecular Formula:
C13H10Cl3N5
Quantity:
Milligrams-Grams
Quality Standard:
In-house standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl
InChI:
InChI=1S/C13H9Cl2N5.ClH/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;/h1-7H,8H2;1H
InChIKey:
MBTJFFMIPPMRGR-UHFFFAOYSA-N
Targets:
Others
Chemical Structure
CAS 899507-36-9 A 438079 hydrochloride

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