BOC Sciences is able to provide the customized lead compounds and preclinical drug candidates to our clients, as well as their profiling and optimization to lead structures and identification of active ingredients for natural products.

Discovery project: BOC Sciences provides the appropriate drug discovery know-how and infrastructure required to advance early-stage projects and yield pharmaceutical leads with strong commercial potential, ready for partnering with industry. The research conducted at Rongene is not a pure fee-for-service, but rather a mixed form of project participation and discovery research – at cost-effective rates and shared low risks.

Drug discovery procedure integrated by the 3“I” platforms (In silico, In Vitro, In Vivo)

Through state-of-the-art techniques, BOC Sciencesis investigating the drug candidates with the following properties:

->Lead Criteria Proof of concept in a relevant therapeutic or mechanistic animal model;

->Clear Mode of Action, as well as sufficient potency and selectivity;

->Clear Structure-Activity Relationship (SAR) and potential for further optimization;

->Appropriate physicochemical, biopharmaceutical and pharmacokinetic properties (SPR);

->Clear strategy for further optimization of the compound properties in the lead optimization phase;

->Intellectual property secured through initial patent applications or clear strategy to achieve Freedom to Operate.