8-Amino-2'-deoxyadenosine - CAS 13389-09-8
Category:
Nucleosides
Product Name:
8-Amino-2'-deoxyadenosine
Catalog Number:
13389-09-8
CAS Number:
13389-09-8
Molecular Weight:
266.26
Molecular Formula:
C10H14N6O3
COA:
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MSDS:
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Structure\Application:
2'-Deoxy-Nucleosides
Chemical Structure
CAS 13389-09-8 8-Amino-2'-deoxyadenosine

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Reference Reading


1.Convenient synthesis of 8-amino-2'-deoxyadenosine.
Frieden M1, Aviñó A, Eritja R. Nucleosides Nucleotides Nucleic Acids. 2003 Feb;22(2):193-202.
We studied the behaviour of 8-azido-2'-deoxyadenosine and 8-bromo-2'-deoxyadenosine in aqueous solutions of ammonia and primary and secondary amines. Unexpectedly, 8-Azido-2'-deoxyadenosine is converted to 8-amino-2'-deoxyadenosine in excellent yields. The use of this reaction for the preparation of 8-aminoadenine derivatives needed for the preparation of oligonucleotides carrying 8-aminoadenine is discussed.