|Synonyms||[(2S,3S,4R)-1-O-(α-D-galactopyranosyl)-N-(11-(4-fluorophenyl)undecanoyl)-2-amino-1,3,4-octadecanetriol)]; N-[(2S,3S,4R)-3,4-dihydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadecan-2-yl]-11-(4-fluorophenyl)undecanamide; 11-(4-Fluorophenyl)-N-[(2s,3s,4r)-1-(Alpha-D-Galactopyranosyloxy)-3,4-Dihydroxyoctadecan-2-Yl]undecanamide; CHEBI:86489; 7DW8-5; 7DW|
|Description||7DW8-5, a novel glycolipid, an analog of α-galactosylceramide (α-GalCer), is an immunostimulate iNKT agonist and a vaccine adjuvant that can harness and amplify the immunotherapeutic potential of NKT cells to treat certain microbial infections such as malaria and HIV. Studies have shown that the adjuvant effect of 7DW8-5 wasmediated by CD1dmolecules.|
Source from the seeds of Schisandra chinensis (Turcz.) Baill, shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffer...
KLS-13019, an azetidine derivative, could be a neuroprotective agent and has been found to exbihit much more effective than cannabidiol.
Brotianide, with anti-fasciolidal activity, is an anthelminthic drug for the treatment of severe infections on animals to remove larvae.
L-carnitine is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyper...
Mitotane, is an antineoplastic medication used in the treatment of adrenocortical carcinoma.
7DW8-5, a novel glycolipid, an analog of α-galactosylceramide (α-GalCer), is an immunostimulate iNKT agonist and a vaccine adjuvant that can harness and amplify...
Sobetirome selectively binds to and activates TRbeta over TRalpha and this receptor selectivity led to the hypothesis that sobetirome would lower cholesterol th...
Dexmecamylamine is a nicotinic channel modulator with antidepressant activity. It demonstrated positive effects in a number of animal models of depression and a...
LY-183648 has antiestrogenic activity. It inhibited PAIII metastasis to the gluteal and iliac lymph nodes.
This active molecular is a potent purine nucleoside phosphorylase inhibitor and a T cell-selective immunosuppressive agent. CI-972 inhibited proliferation of hu...
Schisantherin A, source from the seeds of Schisandra chinensis (Turcz.) Baill., is a mechanism-based inhibitor that not only competitively inhibits but irrevers...
Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.
NSC134754 is a Heat Shock Factor 1 (HSF1) inhibitor. It can induce inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating lig...
AT-584, an azoniatricyclo compound, could have potential biological activity in pharmaceutical studies.
Sortin1 is a synthetic chemical ats as a Sorting inhibitor, redirecting the vacuolar destination of plant carboxypeptidase Y and other proteins in Arabidopsis.
Tetrahydrouridine, a derivative of Uridine, is a potent and reversible competitive inhibitor of cytidine deaminase (CDD) (Ki values = 54 and 240 nM for human an...
Atractylodin is an active component of the essential oil contained in the rhizomes of Atractylodes lancea and A.
Deferasirox effectively chelates iron from Rhizopus oryzae and demonstrates cidal activity in vitro against 28 of 29 clinical isolates of Mucorales at concentra...
Nabumetone is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX.
LY 243670 is a bio-active molecular, but detailed information were not published yet.