|Synonyms||[(2S,3S,4R)-1-O-(α-D-galactopyranosyl)-N-(11-(4-fluorophenyl)undecanoyl)-2-amino-1,3,4-octadecanetriol)]; N-[(2S,3S,4R)-3,4-dihydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadecan-2-yl]-11-(4-fluorophenyl)undecanamide; 11-(4-Fluorophenyl)-N-[(2s,3s,4r)-1-(Alpha-D-Galactopyranosyloxy)-3,4-Dihydroxyoctadecan-2-Yl]undecanamide; CHEBI:86489; 7DW8-5; 7DW|
|Description||7DW8-5, a novel glycolipid, an analog of α-galactosylceramide (α-GalCer), is an immunostimulate iNKT agonist and a vaccine adjuvant that can harness and amplify the immunotherapeutic potential of NKT cells to treat certain microbial infections such as malaria and HIV. Studies have shown that the adjuvant effect of 7DW8-5 wasmediated by CD1dmolecules.|
Procaine hydrochloride is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, an...
Hydroxy Itraconazole, a metabolite of Itraconazole, is a ketoconazole analogue which could be used as an antimycotic.
Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respecti...
CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins. It is often used as a detergent in the solubilization and purification of me...
kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
Sulfoxone sodium is an anti-leprosy drug which was introduced in Japan in 1948.
Neostigmine bromide(Prostigmin) is a reversible acetylcholinesterase inhibitor and a parasympatho-mimetic.
Ritobegron ethyl hydrochloride
Ritobegron is a potential Bladder selectivity of the novel β₃-agonist.
Tolazamide, a sulphonylurea derivative, could be a hypoglycemic agent which is commonly used in Type 2 diabetes.
Osthol is an is a calcium channel blocker, which is found in the plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.
(+)-Cloprostenol isopropyl ester
(+)-Cloprostenol isopropyl ester is a derivative of cloprostenol which has been found to be a FP receptor agonist as well as a luteolytic agent and could be use...
STING agonist; Induces antitumor immunological responses
Nefopam HCl is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline...
p53 and MDM2 proteins-interaction-inhibi
p53 and MDM2 proteins-interaction-inhibitor racemic is an inhibitor of the interaction between p53 and MDM2 proteins.
Cgp 8716 is a major metabolite of GP53,633 which is a basic non-steroidal anti-inflammatory agent Originated by Novartis.
A useful intermediate for chemical synthesis
Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and...
Cantharidin is a natural toxin produced by blister beetles affected the expression of genes associated with DNA damage, cell cycle progression and apoptotic cel...
APC-366, an amino acid derivative, has been found to be a mast cell tryptase inhibitor and was once studied against asthma by Celera Genomics Group. Ki: 7.1 μM.
Neochlorogenic acid is an isomer of chlorogenic acid. It is a natural polyphenolic compound extracted from the flower of Lonicera japonica Thunb. It has resista...