7-CHLOROTHIENO[2,3-F][1,3]BENZODIOXOLE-6-CARBOXYLIC ACID - CAS 334720-22-8
Catalog number: 334720-22-8
Category: Main Product
Molecular Formula:
C10H5ClO4S
Molecular Weight:
256.6623
COA:
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Purity:
95%
Synonyms:
7-CHLOROTHIENO[2,3-F][1,3]BENZODIOXOLE-6-CARBOXYLIC ACID
MSDS:
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InChIKey:
NOPFDJWFUJRYRA-UHFFFAOYSA-N
InChI:
InChI=1S/C10H5ClO4S/c11-8-4-1-5-6(15-3-14-5)2-7(4)16-9(8)10(12)13/h1-2H,3H2,(H,12,13)
Canonical SMILES:
C1OC2=C(O1)C=C3C(=C2)C(=C(S3)C(=O)O)Cl
1.Synthesis, reactions and biological activity of some new thieno[2,3-f]-1,3-benzodioxoles.
Bakhite EA1, Radwan SM. Pharmazie. 1999 Jul;54(7):491-8.
The reaction of 7-chlorothieno[2,3-f]-1,3-benzodioxole-6-carbonyl chloride (2) with some aromatic or heterocyclic amines gave the corresponding 6-(aryl or heterocyclyl) carbamoyl-7-chlorothieno [2,3-f]-1,3-benzodioxoles (3a-c, 4a, b and 5). Compound 2 was also reacted with potassium thiocyanate, ethanol or sodium azide to afford the isothiocyanto compound 6, the ester 7 and the acid azide 9, respectively. Hydrazinolysis of 7 gave the carbohydrazide 8. The compounds 6, 8 and 9 were used as precursors in the synthesis of the target heterocycles, 7-chlorothieno[2,3-f]-1,3-benzodioxoles substituted with a variety of moieties at position-6 (10-15, 17, 19-26, 28-31). Also, 2-methyl-1,3-dixolo[5,6][1]benzothieno[2,3-c]quinolin- 6(5 H)-one (33) was prepared. The antibacterial and antifungal activities of some selected compounds were also reported.
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CAS 334720-22-8 7-CHLOROTHIENO[2,3-F][1,3]BENZODIOXOLE-6-CARBOXYLIC ACID

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