|Description||6-Benzylaminopurine, a purine-based first-generation synthetic cytokinin, could stimulate plant growth.|
The new antitubercular drug candidate 2-[2-S-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one (BTZ043) targets th...
CFLZ-567 is a key intermediate for making carfilzomib. carfilzomib is a selective proteasome inhibitor as an anti-cancer drug.
Remogliflozin etabonat, pro-drug of remogliflozin, is a SGLT2 inhibitor under development for the treatment of type 2 diabetes. Remogliflozin etabonate is a pr...
Ursolic acid is a natural pentacyclic triterpenoid carboxylic acid. It exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50 = 33 μM), does not affect other NAD+-dependent dehydrogenases.
Pidotimod is a synthetic dipeptide molecule with biological and immunological activity on both the adaptive and the innate immune responses.
Duloxetine is a serotonin-norepinephrine reuptake inhibitor (Ki=4.6 nM), used for major depressive disorder, generalized anxiety disorder, fibromyalgia and neur...
ITX-5061 is a scavenger receptor B1 antagonist. Preclinical studies show that ITX-5061 is a selective inhibitor of HCV entry into hepatocytes. It can prevent vi...
Acroteben is a bio-active chemical but no detailed information has been published yet.
Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respecti...
Anti-inflammatory agent. MAPK inhibitor. Inhibits p38, ERK and JNK phosphorylation. Inhibits NFκB activation. Shows antitussive, expectorant and anti-inflammato...
Quetiapine metabolite Quetiapine sulfoxi
Quetiapine metabolite Quetiapine sulfoxide, a metabolite of Quetiapine, has antipsychotic effect.
This active molecular is a cAMP/PKA/CREB pathway activator promoting osteogenic differentiation of human bone marrow derived MSCs in vitro, and it also increase...
GSK376501A is a bio-active chemical compound used for the treatment of type 2 diabetes and hypercholesterolemia. It was developed by GlaxoSmithKline and was onc...
Clamoxyquine, as the pamoate or hydrochloride salt, is an antiamebic and antidiarrheal drug used as a veterinary medicine to treat salmonids for infection with ...
FR-190809 is a potent and orally efficacious ACAT inhibitor potentially for the treatment of Lipoprotein Disorders.
Lomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.
3PO, as a small molecule competitive inhibitor of HIF-1-induced PFKFB3 it has the potential to suppress tumor glucose metabolism and growth of non-small cell lu...
Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.
NSC134754 is a Heat Shock Factor 1 (HSF1) inhibitor. It can induce inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating lig...