6-Azauracil - CAS 461-89-2
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
6-Azauracil
Catalog Number:
461-89-2
Synonyms:
6-Azauracil;461-89-2;1,2,4-Triazine-3,5(2H,4H)-dione;Azauracil;1,2,4-Triazine-3,5-diol;4(6)-Azauracil
CAS Number:
461-89-2
Description:
6-Azauracil inhibits enzymes in nucleoside synthesis and depletes the intracellular GTP/UTP pool. It is being used to identify mutations in transcriptional elongation machinery, as well as mutations in a variety of other pathways.
Molecular Weight:
113.07
Molecular Formula:
C3H3N3O2
Quantity:
Milligrams-Grams
Quality Standard:
Enterprise standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
C1=NNC(=O)NC1=O
InChI:
1S/C3H3N3O2/c7-2-1-4-6-3(8)5-2/h1H,(H2,5,6,7,8)
InChIKey:
SSPYSWLZOPCOLO-UHFFFAOYSA-N
Targets:
Others
Chemical Structure
CAS 461-89-2 6-Azauracil

Related Products


CAS 54350-48-0 Etretinate

Etretinate
(CAS: 54350-48-0)

Etretinate is a second-generation retinoid to treat severe psoriasis. It has been replaced by acitretin, a safer metabolite of etretinate.

CAS 543-82-8 Octodrine

Octodrine
(CAS: 543-82-8)

Octodrine is a local anesthetic and vasoconstrictor, shows leucine aminotransferase inhibition.

BMS-214662 mesylate
(CAS: 474010-58-7)

BMS-214662 mesylate is a potent and selective inhibitor of farnesyltransferase that induces mitochondrial apoptosis in chronic myeloid leukemia stem/progenitor ...

LY 54761
(CAS: 18381-60-7)

CAS 86315-69-7 LY 137150

LY 137150
(CAS: 86315-69-7)

LY 137150 is a bio-active chemical, but no detailed information has been published yet.

6β-Naltrexol Hydrochloride
(CAS: 55488-86-3)

6β-Naltrexol Hydrochloride is a neutral opioid antagonist, as a metabolite of Naltrexone, which is an opioid antagonist.

RVX297
(CAS: 1044871-04-6)

RVX297 is a BD2 selective inhibitor of BET bromodomains. It is structurally related to the clinical compound RVX-208. It has significant implications on differe...

CAS 514-36-3 Fludrocortisone Acetate

Fludrocortisone Acetate
(CAS: 514-36-3)

Fludrocortisone acetate is a synthetic corticosteroid used as a mineralocorticoid.

CAS 4373-41-5 Maslinic acid

Maslinic acid
(CAS: 4373-41-5)

Maslinic acid is a pentacyclic triterpene found in a variety of natural sources. It exerts a wide range of biological activities, such as antitumor, antidiabeti...

CAS 20537-88-6 Amifostine

Amifostine
(CAS: 20537-88-6)

Amifostine is a phosphorylated aminosulfhydryl compound. After dephosphorylation of amifostine by alkaline phosphatase to an active free sulfhydryl (thiol) meta...

CAS 33171-05-0 Bisdemethoxycurcumin

Bisdemethoxycurcumin
(CAS: 33171-05-0)

Bisdemethoxycurcumin is one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflamma...

CAS 60-56-0 Methimazole

Methimazole
(CAS: 60-56-0)

Methimazole (also known as Tapazole or Thiamazole or MMI) is an antithyroid drug,and part of the thioamide group. Like its counterpart propylthiouracil, a major...

Vapreotide acetate
(CAS: 849479-74-9)

Vapreotide is a synthetic somatostatin analog as a Somatotropin receptor antagonist. It can be used for the treatment of esophageal variceal bleeding in patient...

Evogliptin hydrochloride
(CAS: 1246960-27-9)

CAS 108427-72-1 AS-35

AS-35
(CAS: 108427-72-1)

AS-35 is used as an antiallergic drug. It controls allergic diseases by inhibiting eosinophil activation.

FR-900490
(CAS: 105424-59-7)

FR-900490 is a new type of immunoactive substance isolated from Disocia sp. F-11809. It is effective in reversing the damage to bone marrow caused by mitomycin ...

CAS 107668-79-1 Bulleyaconitine A

Bulleyaconitine A
(CAS: 107668-79-1)

Bulleyaconitine A, an active indegrent from aconitum bulleyanum Diel, has been found to be effective in the treatment of chronic pain and rheumatoid arthritis.

CAS 34367-04-9 Ginsenoside Ro

Ginsenoside Ro
(CAS: 34367-04-9)

Ginsenoside Ro, the predominant ginsenoside in the rhizome, shows no hemolytic nor cytotoxic activities.

CAS 37640-71-4 Aprindine

Aprindine
(CAS: 37640-71-4)

Aprindine is a Class 1b antiarrhythmic agent as a cardiac depressant used in arrhythmias.

CAS 18059-10-4 Peiminine

Peiminine
(CAS: 18059-10-4)

Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhi...

Reference Reading


1.Potential antineoplastics I: substituted 3,5-dioxo-and 3-thioxo-5-oxo-2,3,4,5-tetrahydro-1,2,4-triazines.
Ibrahim el-SA, Shams el-Dine SA, Soliman FS, Labouta IM. J Pharm Sci. 1979 Feb;68(2):243-5.
The synthesis of some 6-substituted 3,5-dioxo- and 3-thioxo-5-oxo-2,3,4,5-tetrahydro-1,2,4-triazines for possible antineoplastic activity is reported. The assigned structures were substantiated by IR, NMR, and mass spectral studies of representative members of the series. Four compounds were tested against P-388 lymphocytic leukemia and were inactive.