1.Eicosapentaenoic and docosahexaenoic acids-rich fish oil supplementation attenuates strength loss and limited joint range of motion after eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial.
Tsuchiya Y1, Yanagimoto K2, Nakazato K3, Hayamizu K4, Ochi E5. Eur J Appl Physiol. 2016 Apr 16. [Epub ahead of print]
PURPOSE: This study investigated the effect of eicosapentaenoic and docosahexaenoic acids-rich fish oil (EPA + DHA) supplementation on eccentric contraction-induced muscle damage.
2.Association of faecal elastase 1 with non-fasting triglycerides in type 2 diabetes.
Rathmann W1, Haastert B2, Oscarsson J3, Berglind N3, Lindkvist B4, Wareham NJ5. Pancreatology. 2016 Mar 30. pii: S1424-3903(16)30008-4. doi: 10.1016/j.pan.2016.03.015. [Epub ahead of print]
AIMS: Intestinal absorption of esterified fatty acids depends on exocrine pancreatic function and influences plasma triglycerides levels. The aim was to investigate the association of reduced exocrine pancreatic function (low fecal elastase-1; FE1) with plasma triglycerides in type 2 diabetes and controls without diabetes.
3.Parathyroid hormone levels and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with acetylsalicylic acid and clopidogrel or ticagrelor.
Verdoia M1, Pergolini P2, Rolla R2, Nardin M1, Barbieri L1, Schaffer A1, Bellomo G2, Marino P1, Suryapranata H1, De Luca G1; Novara Atherosclerosis Study Group (NAS). Cardiovasc Ther. 2016 Apr 17. doi: 10.1111/1755-5922.12188. [Epub ahead of print]
BACKGROUND: High on treatment platelet reactivity still represents a challenging issue, potentially vanishing the benefits of dual antiplatelet treatment in patients with coronary artery disease. However, very few is known on the determinants of suboptimal response to antiplatelet agents. Recent interests have emerged on the potential protrombotic effect of parathyroid hormone (PTH). Therefore, the aim of the present study was to assess the impact of parathyroid hormone (PTH) on platelet reactivity in patients receiving DAPT after an acute coronary syndrome or PCI.
4.Non-enzymatic electrochemical biosensor based on Pt NPs/RGO-CS-Fc nano-hybrids for the detection of hydrogen peroxide in living cells.
Bai Z1, Li G2, Liang J1, Su J3, Zhang Y4, Chen H4, Huang Y5, Sui W6, Zhao Y7. Biosens Bioelectron. 2016 Apr 8;82:185-194. doi: 10.1016/j.bios.2016.04.004. [Epub ahead of print]
A highly sensitive non-enzymatic electrochemical sensor based on platinum nanoparticles/reduced graphene oxide-chitosan-ferrocene carboxylic acid nano-hybrids (Pt NPs/RGO-CS-Fc biosensor) was developed for the measurement of hydrogen peroxide (H2O2). The RGO-CS-Fc nano-hybrids was prepared and characterized by UV-vis spectrum, Fourier transform infrared spectroscopy, transmission electron microscopy, Raman spectrometer and electrochemical impedance spectroscopy. Under optimal experimental conditions, the Pt NPs/RGO-CS-Fc biosensor showed outstanding catalytic activity toward H2O2 reduction. The current response of the biosensor presented a linear relationship with H2O2 concentration from 2.0×10-8M to 3.0×10-6M with a correlation coefficient of R2=0.9968 and with logarithm of H2O2 concentration from 6.0×10-6M to 1.0×10-2M with a correlation coefficient of R2=0.9887, the low detection limit of 20nM was obtained at the signal/noise (S/N) ratio of 3.