5-hydroxypyrazine-2-carboxylic acid - CAS 34604-60-9
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
5-hydroxypyrazine-2-carboxylic acid
Catalog Number:
34604-60-9
Synonyms:
4,5-Dihydro-5-oxopyrazinecarboxylic Acid; 5-Hydroxypyrazinecarboxylic Acid; 5-Hydroxypyrazinoic acid; 5-Oxo-4,5-dihydropyrazine-2-carboxylic Acid
CAS Number:
34604-60-9
Description:
A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide.
Molecular Weight:
140.1
Molecular Formula:
C5H4N2O3
COA:
Inquire
MSDS:
Inquire
Targets:
Antibacterial
Chemical Structure
CAS 34604-60-9 5-hydroxypyrazine-2-carboxylic acid

Related Antibacterial Products


CAS 72-80-0 Chlorquinaldol

Chlorquinaldol
(CAS: 72-80-0)

Chlorquinaldol is an antimicrobial agent.

CAS 67-20-9 Nitrofurantoin

Nitrofurantoin
(CAS: 67-20-9)

Nitrofurantoin, an antibioticused to treat urinary tract infections, is not effective for kidney infections.

CAS 22862-76-6 Anisomycin

Anisomycin
(CAS: 22862-76-6)

Anisomycin is an antibiotic, which inhibits protein synthesis, and also act as a JNK activator.

CAS 34642-77-8 Amoxicillin Sodium

Amoxicillin Sodium
(CAS: 34642-77-8)

Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.

CAS 364622-82-2 Doripenem Hydrate

Doripenem Hydrate
(CAS: 364622-82-2)

Doripenem Hydrate is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infection...

CAS 120410-24-4 Biapenem

Biapenem
(CAS: 120410-24-4)

Biapenem (INN) is a carbapenem antibiotic. It has in vitro activity against anaerobes.

CAS 76801-85-9 Azathramycin

Azathramycin
(CAS: 76801-85-9)

Azithromycin, derived from erythromycin, is a antibiotic. It binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. It is an...

CAS 17784-12-2 Sulfacytine

Sulfacytine
(CAS: 17784-12-2)

Sulfacytine, a benzenesulfonamide derivative, could be used as an antibiotic through restraining the formation of folate.

CAS 89786-04-9 Tazobactam acid

Tazobactam acid
(CAS: 89786-04-9)

Tazobactam acid is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commo...

CAS 14769-73-4 Levamisole

Levamisole
(CAS: 14769-73-4)

Levamisole, a thiazole derivative, has been found to be an antibiotic used to against parasitic worm infections and could also have potential activity in antica...

CAS 32886-97-8 Pivmecillinam

Pivmecillinam
(CAS: 32886-97-8)

Pivmecillinam, the pivoxil ester form of penicillin, is active against gram-negative organisms.

CAS 1401-69-0 Tylosin

Tylosin
(CAS: 1401-69-0)

Tylosin is a 16-member-ring macrolide produced through the fermentation of Streptomyces fradiae, a species of actinobacteria found in soil. It is effective agai...

CAS 87239-81-4 Cefpodoxime Proxetil

Cefpodoxime Proxetil
(CAS: 87239-81-4)

Cefpodoxime Proxetil is a third generation cephalosporin, ester prodrug of the active free acid metabolite Cefpodoxime. Cefpodoxime is active against most Gram-...

CAS 74011-58-8 Enoxacin

Enoxacin
(CAS: 74011-58-8)

Enoxacin is an oral broad-spectrum fluoroquinolone antibacterial agent used in the treatment of urinary tract infections and gonorrhea. Insomnia is a common adv...

Alatrofloxacin Mesylate
(CAS: 157605-25-9)

The mesylate salt form of alatrofloxacin, a fluoroquinolone derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed to be...

CAS 1404-90-6 Vancomycin

Vancomycin
(CAS: 1404-90-6)

Tricyclic glycopeptide antibiotic. Inhibits cell wall synthesis in Gram-positive bacteria. Pharmacologically active in vivo.

CAS 98-96-4 Pyrazinamide

Pyrazinamide
(CAS: 98-96-4)

Pyrazinamide is a pyrazine that is used therapeutically as an antitubercular agent. It is a prodrug that stops the growth of Mycobacterium tuberculosis. It was ...

CAS 61379-65-5 Rifapentine

Rifapentine
(CAS: 61379-65-5)

Rifapentine (Priftin) is an semi-synthetic antibiotic compound used in the treatment of tuberculosis.

CAS 141702-36-5 Faropenem daloxate

Faropenem daloxate
(CAS: 141702-36-5)

Faropenem daloxate is useful for penem and antibiotics. Faropenem medoxomil has excellent in vitro activity against Streptococcus pneumoniae, Haemophilus influe...

CAS 141-94-6 Hexetidine

Hexetidine
(CAS: 141-94-6)

Hexetidine, mixture of stereoisomers, is an antibacterial and antifungal agent that destroy fungi by suppressing their ability to grow or reproduce.

Reference Reading


1.Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Pyrazinamide
C. BECKER, J.B. DRESSMAN. JOURNAL OF PHARMACEUTICAL SCIENCES, VOL. 97, NO. 9, SEPTEMBER 2008
The purpose and scope of this series of monographs have been previously discussed. Summarized in few words, the aim is to evaluate all pertinent data available from literature sources for a given API to assess the risks associated with a biowaiver. For these purposes, risk is defined as the probability of an incorrect biowaiver decision as well as the consequences of the decision in terms of public health and individual patient risks. On the basis of these considerations, a recommendation can be made as to whether a biowaiver approval is advisable or not. This systematic approach to recommend or advise against a biowaiver decisions is referred to in the recently published World Health Organization (WHO) Guideline. It is pointed out that these monographs do not simply apply this WHO Guideline, nor the FDA and/or EMEA Guidance, but also want to serve as a critical validation of these regulatory documents. Biowaiver monographs have already been published for acetaminophen (INN: paracetamol), amitriptyline, atenolol, chloroquine, cimetidine, ethambutol, ibuprofen, isoniazid, prednisolone, prednisone, propranolol, ranitidine, and verapamil. They are also available online at the website of the International Pharmaceutical Federation FIP.