|Synonyms||N-(1-benzylpiperidin-4-yl)-4-iodobenzamide (125I)-N-(N-benzylpiperidin-4-yl)-4-iodobenzamide 4-IBP cpd BPIBA N-(N-benzylpiperidin-4-yl)-4-iodobenzamide|
|Description||4-IBP, an agonist that specially targets sigma receptor (IC50= 1.7 nM), induced marked concentration-dependent decreases in the growth of human cancer cells. σ1 receptor: Ki = 1.7 nM; σ2 receptor: Ki = 25.2 nM In vitro: signally decreased the expression o|
PRE-084 hydrochloride is a high affinity, selective receptors exhibiting neuroprotective effects. Its IC50 value is 44 nM in the sigma receptor assay. In vitro,...
Siramesine hydrochloride is the hydrochloride salt form of Siramesine. Siramesine is a selective sigma-2 receptor agonist with a potent anticancer activity in v...
The hydrochloride salt form of S1RA which is a σ1 receptor antagonist that has been found to have potential effect in pain therapy. It is still under Phase II c...
Dextromethorphan is an approved drug with sedative, dissociative, and stimulant properties. It is a cough suppressant in many over-the-counter cold and cough me...
4-IBP, an agonist that specially targets sigma receptor (IC50= 1.7 nM), induced marked concentration-dependent decreases in the growth of human cancer cells. σ1...
Cutamesine, also called as SA4503, is an agonist, small-molecule ligand for the sigma-1 receptor with high selectivity currently in development to mediate neuro...
Siramesine is a selective sigma-2 receptor agonist with a potent anticancer activity in vivo. It was originally devevloped for treating depressant and it has pr...
Noscapine is a phthalideisoquinoline alkaloid derived from the opium poppy Papaver somniferum, with mild analgesic, antitussive, and potential antineoplastic ac...
BD 1047 dihydrobromide
The dihydrobromide salt form of BD-1047, a selective σ1 receptor antagonist, has been found to have antipsychotic effect and could be probably used against schi...
SA-4503 is a potent sigma receptor agonist. SA-4503 may have effects on depressive symptoms such as agitation, loss of interest, and impaired cognition, which a...