4-(Aminomethyl)benzoic Acid - CAS 56-91-7
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
4-(Aminomethyl)benzoic Acid
Catalog Number:
56-91-7
Synonyms:
4-(Aminomethyl)benzoic Acid; Tranexamic Acid Impurity D, α-Amino-p-toluic Acid;
CAS Number:
56-91-7
Description:
4-(Aminomethyl)benzoic Acid, an unnatural amino acid derivative, is a type 2 antifibrinolytic agent,
Molecular Weight:
151.16
Molecular Formula:
C8H9NO2
Quantity:
Grams-Kilos
Quality Standard:
Enterprise Standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
C1=CC(=CC=C1CN)C(=O)O
InChI:
1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)
InChIKey:
QCTBMLYLENLHLA-UHFFFAOYSA-N
Targets:
Others
Chemical Structure
CAS 56-91-7 4-(Aminomethyl)benzoic Acid

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Reference Reading


1.Synthesis of polymer-bound 4-acetoxy-3-phenylbenzaldehyde derivatives: applications in solid-phase organic synthesis.
Kumar A1, Ye G, Ahmadibeni Y, Parang K. J Org Chem. 2006 Sep 29;71(20):7915-8.
Aminomethyl polystyrene resin was reacted with 4-(5'-formyl-2'-hydroxyphenyl)benzoic acid and 4-(5'-formyl-2'-hydroxyphenyl)phenyl propionic acid, respectively, in the presence of 1-hydroxybenzotriazole and 1,3-diisopropylcarbodiimide to yield polymer-bound benzaldehydes. The phenolic group in resins was acetylated with acetic anhydride to afford two polymer-bound 4-acetoxybenzaldehydes. The reductive amination of polymer-bound linkers by amines and sodium triacetoxyborohydride, followed by sulfonylation with arylsulfonyl chloride derivatives in the presence of pyridine and the cleavage with TFA/DCM/H2O, produced pure sulfonamides.