4,6-O-Benzylidene-D-glucose - CAS 30688-66-5
Category:
Carbohydrates
Product Name:
4,6-O-Benzylidene-D-glucose
Catalog Number:
B1999-089803
CAS Number:
30688-66-5
Related CAS:
97232-16-1
Molecular Weight:
268.26
Molecular Formula:
C13H16O6
COA:
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MSDS:
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Structure:
Monosaccharides
Catalog Number Size Price Stock Quantity
B1999-089803 1 g $99 In stock
B1999-089803 100 g $299 In stock
B1999-089803 500 g $798 In stock
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Chemical Structure
CAS 30688-66-5 4,6-O-Benzylidene-D-glucose

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Reference Reading


1.Effect on protein synthesis and cell survival of the benzaldehyde derivatives sodium benzylidene ascorbate (SBA) and the deuterated compound zilascorb(2H).
Pettersen EO1, Larsen RO, Boerretzen B, Dornish JM, Oftebro R. Anticancer Res. 1991 May-Jun;11(3):1077-81.
Three different benzaldehyde derivatives (viz. beta-cyclodextrin benzaldehyde inclusion compound (CDBA), 4, 6-O-benzylidene-D-glucose (BG) and sodium benzylidene-ascorbate (SBA) have been shown to exert anticancer effects in patients without causing side effects. The anticancer effects are, however, variable and in many cases weak. In a previous study we showed that benzaldehyde with a deuterated formyl group gave rise to a greater protein synthesis inhibition than nondeuterated benzaldehyde. Based on this deuterated benzaldehyde we have synthesized an ascorbic acid acetal; 5,6-benzylidene-d1-L-ascorbic acid (zilascorb(2H). In the present paper we compare the effect of this drug with respect to cell inactivation and inhibition of protein synthesis in human cells cultured in vitro with that of benzaldehyde, BG and SBA. It is shown that zilascorb (2H) is clearly the most effective of these drugs. The effect of zilascrob(2H) is reversible in the sense that protein synthesis regains its normal level shortly (i.