|Synonyms||(E)-3-pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one 3PO CHEMBL3105848 13309-08-5 18550-98-6 ZINC03997313 AC1NX4G7 Ambcb5284086 SCHEMBL196639 3PO|3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one (E)-3-(Pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one|
|Description||3PO, as a small molecule competitive inhibitor of HIF-1-induced PFKFB3 it has the potential to suppress tumor glucose metabolism and growth of non-small cell lung cancer cells. in vitro: obviously attenuates the proliferation of several human malignant he|
Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM.
OBA-09 is a novel multimodal neuroprotective agent. It is an ester of pyruvate and salicylic acid that acts as a multi-functional agent to protect against ische...
Hydrastinine hydrochloride is a semisynthetic alkaloid as a haemostatic drug.
This active molecular is an potential cognitive enhancer originated by Bristol-Myers Squibb. Mechanism of Action is not identified. Bmy 21502 is also a nootropi...
Hypaconitine, diterpene alkaloid, is a neuromuscular blocker could inhibit CaM expression and Cx43 (Ser368) phosphorylation. It has anti-inflammatory effect.
Dihydroartemisinin (DHA) is a semi-synthetic derivative of artemisinin and isolated from the traditional Chinese herb Artemisia annua.
AKBA is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.
2-Methyl-2,4-pentanediol, an analog of hexylene glycol, is a small molecular surfactant which could be useful as an environmentally friendly industrial coating ...
Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and can elicit dose-dependent antinocic...
Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM,...
Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
Cryptochlorogenic acid is an isomer of chlorogenic acid. It is a natural product extracted from the flowerbud of Lonicera japonica Thunb. It has antioxidant act...
Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of...
Induces apoptosis. Possible degradation product of taxoid biosynthesis. Anticancer effects.
Arctigenin is the aglycone of arctiin and is a lignan found in certain plants of the Asteraceae. It has shown antiviral and anticancer effects in glass. It show...
LY 186564 is a bio-active chemical,but no detailed information has been published yet.
Stauprimide is an enhancer stem cell differentiation into endoderm. In vitro differentiation of embryonic stem cells is of great interest to regenerative medici...
Flumethasone pivalate is a topical difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. A prompt decrease in...
ECMS is a useful protective group in antibody drug conjugates as a ADCs Linker.
Finerenone is a non-steroidal antimineralocorticoid. It has less relative affinity to other steroid hormone receptors than currently available, which should res...