25-Hydroxy VD2-D6 - CAS 1262843-46-8
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
25-Hydroxy VD2-D6
Catalog Number:
1262843-46-8
Synonyms:
25-Hydroxy VD2-D6
CAS Number:
1262843-46-8
Description:
A labelled metabolite of Vitamin D2
Molecular Weight:
418.68
Molecular Formula:
C28H38D6O2
COA:
Inquire
MSDS:
Inquire
Targets:
VD/VDR
Chemical Structure
CAS 1262843-46-8 25-Hydroxy VD2-D6

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Reference Reading


1.Does serum 25 hydroxy vitamin D level predict disease activity in ulcerative colitis patients?
Dolatshahi S1, Pishgar E1, Jamali R1,2. Acta Clin Belg. 2016 Feb 3:1-5. [Epub ahead of print]
BACKGROUND/AIM: There are controversial results regarding the relationship of serum 25 hydroxy vitamin D [25(OH)D] and ulcerative colitis (UC) activity. To address this issue, the current study was designed to evaluate the correlation of serum 25(OH)D level and disease activity in patients with UC.
2.25-Hydroxy Vitamin D, Vitamin D Receptor and Toll-like Receptor 2 Polymorphisms in Spinal Tuberculosis: A Case-Control Study.
Panwar A1, Garg RK, Malhotra HS, Jain A, Singh AK, Prakash S, Kumar N, Garg R, Mahdi AA, Verma R, Sharma PK. Medicine (Baltimore). 2016 Apr;95(17):e3418. doi: 10.1097/MD.0000000000003418.
Vitamin D deficiency and vitamin D receptor (VDR) gene abnormalities confer susceptibility to tuberculosis. Toll-like receptors (TLRs), such asTLR-2, are also important mediators of inflammatory response against Mycobacterium tuberculosis. We evaluated serum vitamin D, and VDR and TLR-2 gene polymorphisms in patients with spinal tuberculosis.This study comprised of 3 groups: spinal tuberculosis, pulmonary tuberculosis, and controls (each with 106 subjects). Enzyme-linked immunosorbent assay was used to measure vitamin D levels, and polymerase chain reaction-sequencing method was used to analyze VDR and TLR-2 gene polymorphisms. Patients were followed up for 6 months.Vitamin D deficiency was significantly more prevalent in patients with spinal tuberculosis (P < 0.001) and pulmonary tuberculosis (P = 0.011), versus controls. The heterozygous and mutant genotypes of VDR TaqI gene were significantly associated with spinal tuberculosis (P < 0.