1.Combined morphine and limb remote ischemic perconditioning provides an enhanced protection against myocardial ischemia/reperfusion injury by antiapoptosis.
Wang SY1, Cui XL1, Xue FS2, Duan R3, Li RP1, Liu GP1, Yang GZ1, Sun C1. J Surg Res. 2016 May 1;202(1):13-25. doi: 10.1016/j.jss.2015.12.007. Epub 2015 Dec 15.
BACKGROUND: Both morphine and limb remote ischemic perconditioning (RIPer) can protect against myocardial ischemia/reperfusion injury (IRI). This experiment was designed to assess whether combined morphine and limb RIPer could provide and enhanced protection against myocardial IRI in an in vivo rat model.
2.A hydrometallurgical process for recovering total metal values from waste monolithic ceramic capacitors.
Prabaharan G1, Barik SP2, Kumar B1. Waste Manag. 2016 Apr 12. pii: S0956-053X(16)30173-8. doi: 10.1016/j.wasman.2016.04.010. [Epub ahead of print]
A hydrometallurgical process for recovering the total metal values from waste monolithic ceramic capacitors was investigated. The process parameters such as time, temperature, acid concentration, hydrogen peroxide concentration and other reagents (amount of zinc dust and sodium formate) were optimized. Base metals such as Ba, Ti, Sn, Cu and Ni are leached out in two stages using HCl in stage 1 and HCl with H2O2 in stage 2. More than 99% of leaching efficiency for base metals (Cu, Ni, Ba, Ti and Sn) was achieved. Precious metals such as Au and Pd are leached out using aquaregia and nitric acid was used for the leaching of Ag. Base metals (Ba, Ti, Sn, Cu and Ni) are recovered by selective precipitation using H2SO4 and NaOH solution. In case of precious metals, Au and Pd from the leach solution were precipitated out using sodium metabisulphite and sodium formate, respectively. Sodium chloride was used for the precipitation of Ag from leach solution.
3.Preexposure to salty and sour taste enhances conditioned taste aversion to novel sucrose.
Flores VL1, Moran A2, Bernstein M3, Katz DB4. Learn Mem. 2016 Apr 15;23(5):221-8. doi: 10.1101/lm.040360.115. Print 2016 May.
Conditioned taste aversion (CTA) is an intensively studied single-trial learning paradigm whereby animals are trained to avoid a taste that has been paired with malaise. Many factors influence the strength of aversion learning; prominently studied among these is taste novelty-the fact that preexposure to the taste conditioned stimulus (CS) reduces its associability. The effect of exposure to tastes other than the CS has, in contrast, received little investigation. Here, we exposed rats to sodium chloride (N) and citric acid (C), either before or within a conditioning session involving novel sucrose (S). Presentation of this taste array within the conditioning session weakened the resultant S aversion, as expected. The opposite effect, however, was observed when exposure to the taste array was provided in sessions that preceded conditioning: such experience enhanced the eventual S aversion-a result that was robust to differences in CS delivery method and number of tastes presented in conditioning sessions.
4.Development of a microfluidic paper-based analytical device for the determination of salivary aldehydes.
Ramdzan AN1, Almeida MI1, McCullough MJ2, Kolev SD3. Anal Chim Acta. 2016 May 5;919:47-54. doi: 10.1016/j.aca.2016.03.030. Epub 2016 Mar 19.
A low cost, disposable and easy to use microfluidic paper-based analytical device (μPAD) was developed for simple and non-invasive determination of total aldehydes in saliva with a potential to be used in epidemiological studies to assess oral cancer risk. The μPAD is based on the colour reaction between aldehydes (e.g. acetaldehyde, formaldehyde), 3-methyl-2-benzothiazolinone hydrazone (MBTH) and iron(III) to form an intense blue coloured formazan dye. The newly developed μPAD has a 3D design with two overlapping paper layers. The first layer comprises 15 circular detection zones (8 mm in diameter), each impregnated with 8 μL of MBTH, while the second layer contains 15 reagent zones (4 mm in diameter). Two μL of iron(III) chloride are added to each one of the second layer zones after the addition of sample to the detection zones in the first layer. All hydrophilic zones of the μPAD are defined by wax printing using a commercial wax printer.